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1/7/2026 7:09:48 AM | Browse: 1 | Download: 23
Publication Name World Journal of Immunology
Manuscript ID 111511
Country India
Received
2025-07-02 01:39
Peer-Review Started
2025-07-02 01:39
First Decision by Editorial Office Director
2025-08-07 09:15
Return for Revision
2025-08-07 09:15
Revised
2025-08-16 07:14
Publication Fee Transferred
Second Decision by Editor
2025-11-24 02:49
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-11-25 06:32
Articles in Press
2025-11-25 06:32
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-04 09:43
Publish the Manuscript Online
2026-01-07 07:08
ISSN 2219-2824 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology & Pharmacy
Manuscript Type Minireviews
Article Title Preclinical pharmacology studies of zingerone with special reference to potential therapeutic applications
Manuscript Source Invited Manuscript
All Author List Brahmjot Singh, Hasandeep Singh, Sarabjit Kaur and Balbir Singh
Funding Agency and Grant Number
Corresponding Author Balbir Singh, PhD, Professor, Department of Pharmaceutical Sciences, Guru Nanak Dev University, Grand Trunk Road, Off NH 1, Amritsar 143005, Punjab, India. balbir.pharma@gndu.ac.in
Key Words Zingerone; Anti-inflammation; Antioxidant; Anti-proliferative; Antidiabetic
Core Tip Zingerone is one of the potent natural bioactive molecules isolated from the ginger, a natural spice distributes all over the world. In this review, we have identified that zingerone possesses several pharmacological properties such as potent anti-oxidant, anti-inflammatory, anti-apoptotic, antiproliferative effects in pre-clinical studies. These properties suggest that the zingerone is more beneficial in curing several disorders. However, exploration of structure activity relationship could be useful to enhance its stability, safety and effectiveness. Thus, there is a need of future exploration for the therapeutic potential of zingerone in clinical studies. On the basis of literature reviews, it is concluded that zingerone possesses a great potential against various diseases.
Publish Date 2026-01-07 07:08
Citation

Singh B, Singh H, Kaur S, Singh B. Preclinical pharmacology studies of zingerone with special reference to potential therapeutic applications. World J Immunol 2026; 16(1): 111511

URL https://www.wjgnet.com/2219-2824/full/v16/i1/111511.htm
DOI https://dx.doi.org/10.5411/wji.v16.i1.111511
Full Article (PDF) WJI-16-111511-with-cover.pdf
Manuscript File 111511_Auto_Edited_070341.docx
Answering Reviewers 111511-answering-reviewers.pdf
Audio Core Tip 111511-audio.mp3
Conflict-of-Interest Disclosure Form 111511-conflict-of-interest-statement.pdf
Copyright License Agreement 111511-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 111511-non-native-speakers.pdf
Peer-review Report 111511-peer-reviews.pdf
Scientific Misconduct Check 111511-scientific-misconduct-check.png
Scientific Editor Work List 111511-scientific-editor-work-list.pdf
CrossCheck Report 111511-crosscheck-report.pdf