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12/25/2025 9:07:32 AM | Browse: 212 | Download: 466
Publication Name World Journal of Clinical Cases
Manuscript ID 111835
Country China
Received
2025-07-11 05:31
Peer-Review Started
2025-07-11 05:31
First Decision by Editorial Office Director
2025-09-09 09:54
Return for Revision
2025-09-09 09:54
Revised
2025-09-22 11:30
Publication Fee Transferred
2025-09-29 08:17
Second Decision by Editor
2025-12-15 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-15 07:12
Articles in Press
2025-12-15 07:12
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-12-23 01:43
Publish the Manuscript Online
2025-12-25 08:54
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Primary ileal squamous cell carcinoma: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Qian-Qian Li, Jie Wei, Lu-Yao Fang, Jia-Lv Zhou and Huan-Fen Zhao
Funding Agency and Grant Number
Corresponding Author Huan-Fen Zhao, Chief Physician, Professor, Department of Pathology, Hebei General Hospital, No. 348 Heping West Road, Shijiazhuang 050051, Hebei Province, China. hbghbinglike@126.com
Key Words Small intestinal neoplasms; Ileal squamous cell carcinoma; Immunophenotype; Clinical characteristics; Pathogenesis; Clinicopathology; Case report
Core Tip Primary ileal squamous cell carcinoma represents a paradox, as it arises in the ileal mucosa that lacks native squamous epithelium. With an incidence of less than 0.001% among intestinal malignancies and only 12 confirmed cases worldwide (as of 2025), this rare entity remains poorly characterized in the literature. Here, we report a newly diagnosed case of primary ileal squamous cell carcinoma and synthesize its clinicopathologic features, clinical presentation, therapeutic management, and the patient’s outcome and prognosis, with particular emphasis on diagnostic dilemmas and treatment efficacy.
Publish Date 2025-12-25 08:54
Citation

Li QQ, Wei J, Fang LY, Zhou JL, Zhao HF. Primary ileal squamous cell carcinoma: A case report and review of literature. World J Clin Cases 2025; 13(36): 111835

URL https://www.wjgnet.com/2307-8960/full/v13/i36/111835.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i36.111835
Full Article (PDF) 111835-with-cover.pdf