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10/24/2025 10:30:17 AM | Browse: 21 | Download: 61
Publication Name World Journal of Cardiology
Manuscript ID 111870
Country United States
Received
2025-07-11 05:52
Peer-Review Started
2025-07-11 05:53
To Make the First Decision
Return for Revision
2025-07-23 08:40
Revised
2025-08-06 03:44
Second Decision
2025-09-15 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-09-17 10:32
Articles in Press
2025-09-17 10:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-17 02:12
Publish the Manuscript Online
2025-10-24 09:58
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Retrospective Cohort Study
Article Title Frailty status and outcomes of percutaneous coronary intervention in elderly patients with non-ST-elevation myocardial infarction
Manuscript Source Invited Manuscript
All Author List Apurva Popat, Roopeessh Vempati, Lakshmi Sai Meghana Kodali, Alla Sai Santhosha Mrudula, Fadi Haddad, Akhil Jain, Geetha Krishnamoorthy and Param Sharma
Funding Agency and Grant Number
Corresponding Author Roopeessh Vempati, MD, Researcher, Internal Medicine, Trinity Health Oakland/Wayne State University School of Medicine, 44405 Woodward Avenue, Pontiac, MI 48341, United States. roopeessh.vempati@gmail.com
Key Words Acute coronary syndrome; Cardiovascular outcomes; Elderly patients; Frailty; Hospital frailty risk score; In-hospital mortality; National inpatient sample; Percutaneous coronary intervention; Risk stratification
Core Tip This study evaluates how frailty affects the outcomes of percutaneous coronary intervention (PCI) in patients aged ≥ 75 years with non-ST-elevation myocardial infarction. Using the Hospital Frailty Risk Score, we found that PCI is associated with a reduction in in-hospital mortality across all frailty categories. However, the benefits of PCI decrease as frailty increases, while complications and healthcare utilization significantly rise. These findings emphasize the need for individualized treatment strategies. While frailty should not prevent PCI, it should be considered in shared decision-making to balance the survival benefits against the procedural risks and resource demands in this high-risk population.
Publish Date 2025-10-24 09:58
Citation <p>Popat A, Vempati R, Kodali LSM, Sai Santhosha Mrudula A, Haddad F, Jain A, Krishnamoorthy G, Sharma P. Frailty status and outcomes of percutaneous coronary intervention in elderly patients with non-ST-elevation myocardial infarction. <i>World J Cardiol</i> 2025; 17(10): 111870</p>
URL https://www.wjgnet.com/1949-8462/full/v17/i10/111870.htm
DOI https://dx.doi.org/10.4330/wjc.v17.i10.111870
Full Article (PDF) WJC-17-111870-with-cover.pdf
STROBE Statement 111870-STROBE-statement.pdf
Manuscript File 111870_Auto_Edited_095938.docx
Answering Reviewers 111870-answering-reviewers.pdf
Audio Core Tip 111870-audio.m4a
Biostatistics Review Certificate 111870-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 111870-conflict-of-interest-statement.pdf
Copyright License Agreement 111870-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 111870-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 111870-institutional-review-board-statement.pdf
Supplementary Material 111870-supplementary-material.pdf
Peer-review Report 111870-peer-reviews.pdf
Scientific Misconduct Check 111870-scientific-misconduct-check.png
Scientific Editor Work List 111870-scientific-editor-work-list.pdf
CrossCheck Report 111870-crosscheck-report.pdf