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11/27/2025 10:24:49 AM | Browse: 19 | Download: 86
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Received |
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2025-07-17 03:11 |
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Peer-Review Started |
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2025-07-17 03:12 |
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To Make the First Decision |
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Return for Revision |
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2025-07-30 07:25 |
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Revised |
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2025-08-11 17:37 |
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Second Decision |
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2025-09-04 02:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-09-04 07:39 |
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Articles in Press |
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2025-09-04 07:39 |
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Publication Fee Transferred |
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2025-08-15 01:31 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-18 05:51 |
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Publish the Manuscript Online |
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2025-11-27 09:20 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Basic Study |
| Article Title |
Investigating the pharmaceutical substances and action mechanisms of Changmaxifeng granules against tic disorders
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Dong Xie, Jian-Ping Wu, Shu-Sen Liu, Zheng Zong, Yang Hu, Na Ling, Bing Han, Wen-Lan Li and Hong-Yan Yao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key Research and Development Plan Project of Heilongjiang Province |
2022ZX02C08 |
| Heilongjiang Science and Technology Talent Spring Swallow Support Program Project |
CYCX24009 |
| 2025 Graduate Innovation Research Funding Project of Harbin University of Commerce |
YJSCX2025-833HSD |
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| Corresponding Author |
Wen-Lan Li, Professor, School of Pharmacy, Harbin University of Commerce, No. 138 Tongda Street, Daoli District, Harbin 150076, Heilongjiang Province, China. lwldzd@163.com |
| Key Words |
Changmaxifeng granule; Against tic disorders; Chemical components; Network pharmacology; Molecular docking |
| Core Tip |
Clinical studies have shown that Changmaxifeng granules (CG) can treat tic disorders. However, the pharmaceutical substances and mechanism of action of CG remain unclear. In this study, we combined serum pharmacochemistry with network pharmacology to identify the chemical constituents of CG that enter the bloodstream and to predict their potential molecular targets, thereby laying the groundwork for elucidating the underlying mechanisms of action. |
| Publish Date |
2025-11-27 09:20 |
| Citation |
<p>Xie LD, Wu JP, Liu SS, Zong Z, Hu Y, Ling N, Han B, Li WL, Yao HY. Investigating the pharmaceutical substances and action mechanisms of Changmaxifeng granules against tic disorders. <i>World J Psychiatry</i> 2025; 15(12): 112055</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i12/112055.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i12.112055 |
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