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3/15/2026 6:29:16 AM | Browse: 2 | Download: 0
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Received |
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2025-07-16 09:30 |
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Peer-Review Started |
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2025-07-16 09:31 |
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First Decision by Editorial Office Director |
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2025-07-25 07:03 |
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Return for Revision |
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2025-07-25 07:03 |
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Revised |
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2025-08-06 20:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-05 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-05 09:40 |
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Articles in Press |
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2026-01-05 09:40 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-04 00:27 |
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Publish the Manuscript Online |
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2026-03-15 06:09 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Case Control Study |
| Article Title |
Diagnostic utility of circulating interleukin-1 beta and microRNA-146a in differentiating febrile seizures from other pediatric conditions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Saeed Mohammadi, Mwssa Abbood Hameed Ati, Fakhri Sadat Seyedhosseini, Mojtaba Zare Ebrahimabad, Mohsen Saeidi, Seyed Ahmad Hosseini, Mahmoud Darweesh, Ahmed Al-Harrasi and Yaghoub Yazdani |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Golestan University of Medical Sciences |
No. 113610 |
| Oman Ministry of Higher Education, Research, and Innovation |
No. BFP/RGP/HSS/24/015 |
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| Corresponding Author |
Yaghoub Yazdani, Laboratory Sciences Research Center, Golestan University of Medical Sciences, Hirkania BLVD, Gorgan 4934174515, Golestān, Iran. yazdani@goums.ac.ir |
| Key Words |
Febrile seizure; Biomarkers; Interleukin-1 beta; MicroRNA-146a; Diagnostic utility; Healthy subjects; Fever-only; Seizure-only |
| Core Tip |
This study assessed the diagnostic potential of interleukin-1 beta (IL1-β) and microRNA-146a in distinguishing febrile seizures (FS) from healthy subjects, fever-only, and seizure-only cases. Interleukin-1 beta levels were significantly highest in the FS group, while microRNA-146a levels were lowest in FS and highest in healthy subjects. Both markers demonstrated high diagnostic accuracy in differentiating FS from the other groups, suggesting they are promising diagnostic biomarkers for FS and support the role of neuroinflammation in FS development. |
| Publish Date |
2026-03-15 06:09 |
| Citation |
Mohammadi S, Abbood Hameed Ati M, Seyedhosseini FS, Zare Ebrahimabad M, Saeidi M, Hosseini SA, Darweesh M, Al-Harrasi A, Yazdani Y. Diagnostic utility of circulating interleukin-1 beta and microRNA-146a in differentiating febrile seizures from other pediatric conditions. World J Exp Med 2026; 16(1): 112061 |
| URL |
https://www.wjgnet.com/2220-315x/full/v16/i1/112061.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v16.i1.112061 |
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