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11/14/2025 7:59:13 AM | Browse: 98 | Download: 203
Publication Name World Journal of Orthopedics
Manuscript ID 112198
Country Saudi Arabia
Received
2025-07-21 01:08
Peer-Review Started
2025-07-21 01:08
First Decision by Editorial Office Director
2025-08-08 08:58
Return for Revision
2025-08-08 08:58
Revised
2025-08-21 16:33
Publication Fee Transferred
2025-09-05 07:38
Second Decision by Editor
2025-10-24 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-24 08:50
Articles in Press
2025-10-24 08:50
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-11-07 01:24
Publish the Manuscript Online
2025-11-14 07:35
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Minireviews
Article Title Shoulder complications in sickle cell disease: Challenges, management strategies, and future directions
Manuscript Source Unsolicited Manuscript
All Author List Emad Anam
Funding Agency and Grant Number
Corresponding Author Emad Anam, Assistant Professor, FRCS, Department of Orthopedic Surgery, Faculty of Medicine, King Abdulaziz University, 7053 Alfyha dist, Jeddah 33335, Saudi Arabia. em2009@hotmail.com
Key Words Core decompression.; Osteomyelitis; Arthroplasty; Avascular necrosis; Shoulder; Sickle cell disease
Core Tip This comprehensive narrative review highlights the challenges of managing shoulder complications in sickle cell disease (SCD) which discusses a critical and underexplored part of this disease. The review synthesizes current evidence on the three primary complications avascular necrosis, osteomyelitis, and septic arthritis. SCD lead to chronic hemolysis and vaso-occlousive crisis contribute to ischemic damage, with humeral head avascular necrosis often underdiagnosed due to overlapping symptoms with other conditions. Early diagnosis and differentiation rely on advanced imaging and laboratory tests. Management includes pain control, core decompression for early stages, and arthroplasty for advanced cases. Given the scarcity of research on shoulder pathology in SCD, larger, long-term studies are needed to refine treatment strategies and improve patient outcomes.
Publish Date 2025-11-14 07:35
Citation

Anam E. Shoulder complications in sickle cell disease: Challenges, management strategies, and future directions. World J Orthop 2025; 16(11): 112198

URL https://www.wjgnet.com/2218-5836/full/v16/i11/112198.htm
DOI https://dx.doi.org/10.5312/wjo.v16.i11.112198
Full Article (PDF) WJO-16-112198-with-cover.pdf
Manuscript File 112198_Auto_Edited_015701.docx
Answering Reviewers 112198-answering-reviewers.pdf
Audio Core Tip 112198-audio.m4a
Conflict-of-Interest Disclosure Form 112198-conflict-of-interest-statement.pdf
Copyright License Agreement 112198-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 112198-non-native-speakers.pdf
Peer-review Report 112198-peer-reviews.pdf
Scientific Misconduct Check 112198-scientific-misconduct-check.png
Scientific Editor Work List 112198-scientific-editor-work-list.pdf
CrossCheck Report 112198-crosscheck-report.pdf