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12/3/2025 9:14:51 AM | Browse: 18 | Download: 50
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Received |
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2025-07-23 03:14 |
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Peer-Review Started |
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2025-07-23 03:14 |
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First Decision by Editorial Office Director |
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2025-08-19 09:57 |
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Return for Revision |
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2025-08-19 09:57 |
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Revised |
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2025-08-29 05:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-10-27 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-27 06:20 |
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Articles in Press |
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2025-10-27 06:20 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-20 10:16 |
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Publish the Manuscript Online |
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2025-12-03 09:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Minireviews |
| Article Title |
Organ preservation in esophageal cancer treatment, is it time now?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jia-Hang Xu and Yong Liu |
| Funding Agency and Grant Number |
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| Corresponding Author |
Yong Liu, Chief Physician, MD, Department of Thoracic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, No. 26 Shengli Street, Wuhan 430011, Hubei Province, China. liuyong7575@163.com |
| Key Words |
Esophageal carcinoma; Neoadjuvant chemoradiotherapy; Immunotherapy; Organ preservation; Randomized clinical trial; Clinical complete response; Active surveillance |
| Core Tip |
Esophageal cancer (EC) ranks among the most prevalent malignant tumors worldwide. Organ preservation (OP) therapy aims to optimize patient quality of life without compromising survival outcomes. Recent advances in endoscopic techniques and immunotherapy have significantly improved the safety and feasibility of OP strategies for EC. However, the widespread implementation of OP remains limited by several challenges. These include discrepancies between clinical complete response and pathological complete response assessments, uncertainties regarding long-term safety, and the absence of standardized patient selection criteria. Future efforts should focus on enhancing the predictive accuracy of treatment response, optimizing active surveillance protocols, strategically integrating immunotherapy into neoadjuvant frameworks, and validating these approaches through rigorously designed, sufficiently powered, multicenter randomized controlled trials. |
| Publish Date |
2025-12-03 09:10 |
| Citation |
Xu JH, Liu Y. Organ preservation in esophageal cancer treatment, is it time now? World J Gastroenterol 2025; 31(45): 112287 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i45/112287.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i45.112287 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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