| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Nutrition & Dietetics |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Multistrain probiotics alleviate gastrointestinal symptoms during bismuth quadruple therapy for Helicobacter pylori infection
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Jun Liu, Yue-Ming Zhao, Qing-Qing Xie, Min-Chan Wu, Yun-Feng Pan, Hao-Kun Yan, Xiao-Xi Shan, Wen-Ting Xu, Yang-Ling Liu, Cai-Xia Peng, Xiao-Mei Zhang and Qian Lin |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Hyproca Nutrition Co., Ltd. |
|
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| Corresponding Author |
Qian Lin, MD, PhD, Professor, Department of Nutrition Science and Food Hygiene, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410078, Hunan Province, China. linqian@csu.edu.cn |
| Key Words |
Helicobacter pylori infection; Bismuth quadruple therapy; Multistrain probiotics; Gastrointestinal symptoms; Randomised controlled trial |
| Core Tip |
In this randomized, double-blind, placebo-controlled trial involving 174 adults, a 4-week multistrain probiotics formula mainly containing five Bifidobacterium and Lactobacillus species added to bismuth quadruple therapy for Helicobacter pylori infection significantly reduced reflux, dyspepsia and diarrhea scores at weeks 4-8 without affecting eradication rates. Probiotics are a safe adjunct to ease antibiotic-associated gastrointestinal symptoms. |
| Publish Date |
2025-11-13 06:51 |
| Citation |
<p>Liu WJ, Zhao YM, Xie QQ, Wu MC, Pan YF, Yan HK, Shan XX, Xu WT, Liu YL, Peng CX, Zhang XM, Lin Q. Multistrain probiotics alleviate gastrointestinal symptoms during bismuth quadruple therapy for Helicobacter pylori infection. <i>World J Gastroenterol</i> 2025; 31(42): 112577</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i42/112577.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i42.112577 |
