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12/4/2025 8:55:22 AM | Browse: 7 | Download: 53
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Received |
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2025-08-05 09:34 |
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Peer-Review Started |
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2025-08-05 09:35 |
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First Decision by Editorial Office Director |
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2025-08-27 06:45 |
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2025-08-27 06:45 |
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Revised |
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2025-09-08 15:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-26 02:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-26 11:35 |
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Articles in Press |
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2025-11-26 11:35 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-02 00:34 |
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Publish the Manuscript Online |
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2025-12-04 06:40 |
| ISSN |
1949-8454 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Interferon-gamma signaling pathway: Modulation of key genes in the progression of glioblastoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Enrique Oropeza-Martínez, Eva G Palacios Serrato, Sayra X Zamora-Salas, Norma A Lira-Rodríguez, Siankaan HZ López-Mignon, Maximo B Martinez-Benitez and Angeles C Tecalco-Cruz |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Colegio de Ciencia y Tecnología de la Universidad Autónoma de la Ciudad de México |
CCYT-2025-CON-11 |
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| Corresponding Author |
Angeles C Tecalco-Cruz, Full Professor, PhD, Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Colonia Del valle, San Lorenzo 290, Mexico 03100, Mexico. angeles.tecalco@uacm.edu.mx |
| Key Words |
Glioblastoma; Interferon gamma; Janus kinases; Interferon-stimulated genes; Signal transducer and activator of transcription 1; Interferon regulatory factor 1; B7-H1 antigen; Indoleamine-2,3-dioxygenase; Interferon-stimulated gene 15; Signal transduction |
| Core Tip |
This review examines the characteristics and functions of five genes induced by interferon-gamma—signal transducer and activator of transcription 1, interferon regulatory factor 1, programmed death-ligand 1, indoleamine 2,3-dioxygenase 1, and interferon-stimulated gene 15—that participate in various mechanisms that promote glioblastoma, a highly aggressive brain tumor; therefore, investigating these genes could contribute to the identification of potential biomarkers and therapeutic targets. |
| Publish Date |
2025-12-04 06:40 |
| Citation |
Oropeza-Martínez E, Palacios Serrato EG, Zamora-Salas SX, Lira-Rodríguez NA, López-Mignon SH, Martinez-Benitez MB, Tecalco-Cruz AC. Interferon-gamma signaling pathway: Modulation of key genes in the progression of glioblastoma. World J Biol Chem 2025; 16(4): 112768 |
| URL |
https://www.wjgnet.com/1949-8454/full/v16/i4/112768.htm |
| DOI |
https://dx.doi.org/10.4331/wjbc.v16.i4.112768 |
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