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12/3/2025 9:14:52 AM | Browse: 21 | Download: 46
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Received |
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2025-08-11 06:23 |
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Peer-Review Started |
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2025-08-11 06:24 |
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First Decision by Editorial Office Director |
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2025-08-20 08:17 |
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2025-08-20 08:17 |
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Revised |
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2025-09-03 03:56 |
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Publication Fee Transferred |
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2025-09-06 00:53 |
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Second Decision by Editor |
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2025-10-22 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-10-22 06:24 |
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Articles in Press |
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2025-10-22 06:24 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-11-27 02:35 |
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Publish the Manuscript Online |
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2025-12-03 09:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Complete blood counts and their derived inflammatory markers with anal fistulas in male children: A retrospective case-control study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Huang-Fu Ma, Yi-Hao Chen, Yue Wang, Xue-Cheng Zhang, Jia-Nan Li, Yan-Mei Wang and Zhang-Yun Zhou |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| China-Japan Friendship Hospital Scientific Research Fund |
No. 2024-ZF-31 |
| China-Japan Friendship Hospital Scientific Research Fund |
No. 2024-ZF-12 |
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| Corresponding Author |
Huang-Fu Ma, Department of Proctology, China-Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing 100029, China. mahuangfu@zryhyy.com.cn |
| Key Words |
Complete blood count; Diagnostic performance; Inflammatory biomarkers; Pediatric perianal fistula; Male children |
| Core Tip |
This retrospective case-control study analyzed 974 male infants and toddlers, including 681 with pediatric fistula-in-ano (PFIA) and 293 healthy controls, to assess the relationship between complete blood count-derived inflammatory markers and PFIA. Patients showed higher lymphocyte counts but lower monocyte-to-lymphocyte ratio (MLR) and systemic inflammatory response index (SIRI) levels, which remained significant after age adjustment. Lymphocyte count, MLR, and SIRI demonstrated strong predictive value and clinical utility for PFIA detection and prognosis. The number of fistula tracts correlated with these markers. Lymphocyte count may serve as a useful biomarker, supporting early diagnosis and targeted prevention in pediatric PFIA. |
| Publish Date |
2025-12-03 09:10 |
| Citation |
Ma HF, Chen YH, Wang Y, Zhang XC, Li JN, Wang YM, Zhou ZY. Complete blood counts and their derived inflammatory markers with anal fistulas in male children: A retrospective case-control study. World J Gastroenterol 2025; 31(45): 112926 |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i45/112926.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i45.112926 |
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