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12/25/2025 9:24:08 AM | Browse: 12 | Download: 17
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Received |
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2025-09-03 06:06 |
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Peer-Review Started |
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2025-09-03 06:06 |
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First Decision by Editorial Office Director |
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2025-09-16 09:17 |
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Return for Revision |
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2025-09-16 09:17 |
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Revised |
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2025-09-30 12:33 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-11-21 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-11-21 10:05 |
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Articles in Press |
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2025-11-21 10:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-12-18 03:08 |
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Publish the Manuscript Online |
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2025-12-25 03:52 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dermatology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Advancing human adipose-derived mesenchymal stem cell-derived exosomes for androgenetic alopecia: Appraisal and methodological recommendations
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu Jiang, Wen-Jun Huang and Rui Zhou |
| Funding Agency and Grant Number |
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| Corresponding Author |
Rui Zhou, Associate Professor, PhD, Shaanxi Institute for Pediatric Diseases, Affiliated Children’s Hospital of Xi’an Jiaotong University, No. 69 West Juyuan Lane, Lianhu District, Xi’an 710003, Shaanxi Province, China. zhouhuaxizhu@126.com |
| Key Words |
Androgenetic alopecia; Extracellular vesicles; Human adipose-derived mesenchymal stem cell-derived exosomes; CDC42; Wnt/β-catenin signaling; Quality control; Dermal papilla cells |
| Core Tip |
Key challenges for translating human adipose-derived mesenchymal stem cell-derived exosomes in androgenetic alopecia include: Incomplete exosome marker information; lack of standardized reporting for particle counts and protein content; absence of direct CDC42 function validation; limited depth in Wnt/β-catenin pathway analysis; insufficient biochemical data in animal models; undefined microneedle delivery parameters; limited safety profiling; and lack of integrated quality control and potency release criteria. |
| Publish Date |
2025-12-25 03:52 |
| Citation |
Jiang Y, Huang WJ, Zhou R. Advancing human adipose-derived mesenchymal stem cell-derived exosomes for androgenetic alopecia: Appraisal and methodological recommendations. World J Stem Cells 2025; 17(12): 113456 |
| URL |
https://www.wjgnet.com/1948-0210/full/v17/i12/113456.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i12.113456 |
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