Publication Name	World Journal of Clinical Cases
Manuscript ID	113560
Country	Japan

Received	2025-08-29 05:36
Peer-Review Started	2025-08-29 05:36
To Make the First Decision
Return for Revision	2025-09-12 06:32
Revised	2025-09-25 08:34
Second Decision	2025-11-05 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-11-05 05:49
Articles in Press	2025-11-05 05:49
Publication Fee Transferred	2025-09-26 05:24
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-11-14 00:21
Publish the Manuscript Online	2025-11-21 03:54

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Toxicology
Manuscript Type	Case Report
Article Title	Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Kurumi Mori, Yoshito Kamijo, Tomoki Doi, Hiroko Abe and Ichiro Takeuchi
Funding Agency and Grant Number
Corresponding Author	Kurumi Mori, Department of Emergency and Critical Care Medicine, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama 232-0024, Kanagawa, Japan. e123082b@yokohama-cu.ac.jp
Key Words	Venlafaxine; Massive ingestion; QTc prolongation; Veno-arterial extracorporeal membrane oxygenation; Ventricular fibrillation; Case report
Core Tip	A 31-year-old woman ingested a massive dose of venlafaxine (14.8 g) and initially showed only mild QTc prolongation. However, she developed ventricular fibrillation 15 hours post-ingestion. She was successfully managed with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This case highlights the potential for delayed but life-threatening cardiotoxicity in venlafaxine overdose and demonstrates the utility of VA-ECMO as a life-saving intervention. Continuous electrocardiographic monitoring beyond the early phase is essential even when initial findings are mild.
Publish Date	2025-11-21 03:54
Citation	<p>Mori K, Kamijo Y, Doi T, Abe H, Takeuchi I. Severe venlafaxine poisoning successfully rescued with veno-arterial extracorporeal membrane oxygenation: A case report. <i>World J Clin Cases</i> 2025; 13(33): 113560</p>
URL	https://www.wjgnet.com/2307-8960/full/v13/i33/113560.htm
DOI	https://dx.doi.org/10.12998/wjcc.v13.i33.113560

Full Article (PDF)	WJCC-13-113560-with-cover.pdf
CARE Checklist–2016	113560-CARE-Checklist-2016.pdf
Manuscript File	113560_Auto_Edited_021831.docx
Answering Reviewers	113560-answering-reviewers.pdf
Audio Core Tip	113560-audio.m4a
Conflict-of-Interest Disclosure Form	113560-conflict-of-interest-statement.pdf
Copyright License Agreement	113560-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s)	113560-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate	113560-non-native-speakers.pdf
Peer-review Report	113560-peer-reviews.pdf
Scientific Misconduct Check	113560-scientific-misconduct-check.png
Scientific Editor Work List	113560-scientific-editor-work-list.pdf
CrossCheck Report	113560-crosscheck-report.pdf