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11/6/2025 9:06:02 AM | Browse: 12 | Download: 13
Publication Name World Journal of Gastroenterology
Manuscript ID 113736
Country Australia
Received
2025-09-02 04:55
Peer-Review Started
2025-09-02 04:55
To Make the First Decision
Return for Revision
2025-09-22 09:48
Revised
2025-09-23 11:55
Second Decision
2025-10-09 01:11
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-10-09 01:40
Articles in Press
2025-10-09 01:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-10-24 01:55
Publish the Manuscript Online
2025-11-06 08:56
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Sirolimus and gastrointestinal angiodysplasia: Can an established agent change the way gastrointestinal bleeding is managed?
Manuscript Source Invited Manuscript
All Author List Robert Sean O'Neill, Jeyvin Nandakumaran and Robert Feller
Funding Agency and Grant Number
Corresponding Author Robert Sean O'Neill, Department of Gastroenterology and Hepatology, Campbelltown Hospital, Therry Road, Campbelltown 2560, New South Wales, Australia. rone1111@outlook.com
Key Words Gastroenterology; Angiodysplasia; Gastrointestinal bleeding; Sirolimus; Bleeding
Core Tip This article discussed the current treatment landscape of gastrointestinal angiodysplasia (GIAD) with a focus on pharmacological management rather than endoscopic management. It also examines the study by Sun et al, who demonstrated in their small single-centre study that sirolimus, a mammalian target of rapamycin inhibitor, reduced bleeding and transfusion needs while improving haemoglobin levels in GIAD patients.
Publish Date 2025-11-06 08:56
Citation <p>O'Neill RS, Nandakumaran J, Feller R. Sirolimus and gastrointestinal angiodysplasia: Can an established agent change the way gastrointestinal bleeding is managed? <i>World J Gastroenterol</i> 2025; 31(41): 113736</p>
URL https://www.wjgnet.com/1007-9327/full/v31/i41/113736.htm
DOI https://dx.doi.org/10.3748/wjg.v31.i41.113736
Full Article (PDF) WJG-31-113736-with-cover.pdf
Manuscript File 113736_Auto_Edited_015745.docx
Answering Reviewers 113736-answering-reviewers.pdf
Audio Core Tip 113736-audio.mp3
Conflict-of-Interest Disclosure Form 113736-conflict-of-interest-statement.pdf
Copyright License Agreement 113736-copyright-assignment.pdf
Peer-review Report 113736-peer-reviews.pdf
Scientific Misconduct Check 113736-scientific-misconduct-check.png
Scientific Editor Work List 113736-scientific-editor-work-list.pdf
CrossCheck Report 113736-crosscheck-report.pdf