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3/10/2026 8:21:51 AM | Browse: 0 | Download: 0
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Received |
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2025-09-05 09:00 |
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Peer-Review Started |
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2025-09-05 09:00 |
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First Decision by Editorial Office Director |
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2025-09-29 07:30 |
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Return for Revision |
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2025-10-01 04:59 |
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Revised |
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2025-10-09 19:53 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-11 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-11 06:32 |
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Articles in Press |
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2025-12-11 06:32 |
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Edit the Manuscript by Language Editor |
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2025-12-18 02:56 |
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Typeset the Manuscript |
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2026-02-28 06:54 |
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Publish the Manuscript Online |
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2026-03-10 06:59 |
| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Metabolic dysfunction-associated fatty liver disease: A key player in colorectal cancer development and progression
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yasser Fouad, Ziyan Pan, Alaa M Mostafa and Mohammed Eslam |
| Funding Agency and Grant Number |
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| Corresponding Author |
Yasser Fouad, MD, Professor, Department of Gastroenterology, Hepatology and Endemic Medicine, Faculty of Medicine, Minia University, El-Horria Stree, Minia 19111, Egypt. yasser.abdallah@mu.edu.eg |
| Key Words |
Metabolic associated fatty liver disease; Colorectal carcinoma; Risk factors; Colon; Liver |
| Core Tip |
Metabolic dysfunction-associated fatty liver disease may actively contribute to the development, progression, and outcomes of colorectal cancer in addition to coexisting with it, according to mounting epidemiological and mechanistic evidence. Obesity, type 2 diabetes, dietary patterns, and systemic inflammation are among the risk factors that overlap between the two conditions, indicating a convergent pathophysiological axis. Changing one’s lifestyle, controlling metabolic risk factors, and using new therapeutic targets like anti-inflammatory and antifibrotic drugs may help slow the progression of metabolic dysfunction-associated fatty liver disease and lower the burden of colorectal cancer. This perspective emphasises the necessity of multidisciplinary strategies aimed at prevention, early detection, and therapeutic optimisation. |
| Publish Date |
2026-03-10 06:59 |
| Citation |
Fouad Y, Pan Z, Mostafa AM, Eslam M. Metabolic dysfunction-associated fatty liver disease: A key player in colorectal cancer development and progression. World J Meta-Anal 2026; 14(1): 113789 |
| URL |
https://www.wjgnet.com/2308-3840/full/v14/i1/113789.htm |
| DOI |
https://dx.doi.org/10.13105/wjma.v14.i1.113789 |
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