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3/19/2026 7:46:56 AM | Browse: 108 | Download: 111
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Received |
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2025-09-08 10:35 |
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Peer-Review Started |
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2025-09-08 10:36 |
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First Decision by Editorial Office Director |
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2025-10-11 07:20 |
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Return for Revision |
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2025-10-11 07:20 |
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Revised |
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2025-10-24 17:33 |
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Publication Fee Transferred |
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2025-10-28 14:23 |
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Second Decision by Editor |
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2026-01-28 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-28 09:21 |
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Articles in Press |
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2026-01-28 09:21 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-06 00:10 |
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Publish the Manuscript Online |
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2026-03-19 07:07 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xu Han, Miao-Yang Chen, Qing-Fang Xiong, Yan-Dan Zhong, Du-Xian Liu, Jia Li and Yong-Feng Yang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81970454 |
| Key Projects of Jiangsu Provincial Health Commission |
ZD2021061 |
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| Corresponding Author |
Yong-Feng Yang, Chief Physician, PhD, Professor, Department of Infectious Disease and Liver Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, No. 1 Zhongfu Road, Gulou District, Nanjing 210003, Jiangsu Province, China. yangyongfeng@njucm.edu.cn |
| Key Words |
Metabolic dysfunction-associated steatotic liver disease; Metabolic dysfunction-associated steatohepatitis; Ballooned hepatocytes; Cytokeratin 8/18; Sonic hedgehog |
| Core Tip |
This is a retrospective cohort study of the characteristics of metabolic dysfunction-associated steatohepatitis, in which we found the suggestive role of sonic hedgehog immunostaining in the diagnosis of metabolic dysfunction-associated steatohepatitis. We also found that histological ballooning hepatocytes and circulating M30 as independent predictors of advanced fibrosis. |
| Publish Date |
2026-03-19 07:07 |
| Citation |
Han X, Chen MY, Xiong QF, Zhong YD, Liu DX, Li J, Yang YF. Role of hepatic sonic hedgehog protein expression in the diagnosis of metabolic dysfunction-associated steatohepatitis. World J Gastroenterol 2026; 32(12): 113939 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i12/113939.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i12.113939 |
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