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3/12/2026 9:31:56 AM | Browse: 10 | Download: 7
Publication Name World Journal of Diabetes
Manuscript ID 113947
Country China
Received
2025-09-08 06:24
Peer-Review Started
2025-09-12 00:15
First Decision by Editorial Office Director
2025-10-23 08:13
Return for Revision
2025-10-23 08:13
Revised
2025-10-25 10:36
Publication Fee Transferred
Second Decision by Editor
2025-12-18 02:52
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-25 07:59
Articles in Press
2025-12-25 07:59
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-26 09:03
Publish the Manuscript Online
2026-03-12 09:18
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Basic Study
Article Title SLC30A8 promoter hypermethylation is associated with type 2 diabetes and diabetic kidney disease in a Chinese population
Manuscript Source Unsolicited Manuscript
All Author List Nan Li, Yu-Peng Li, Qing Xu, Jian Xu, Yi-Hong Yu, Juan Su, Chong Shen, Jiang-Yi Yu and Harvest F Gu
Funding Agency and Grant Number
Funding Agency Grant Number
Excellent Doctor Program of Jiangsu Province Hospital of Chinese Medicine 20221222
Launch Grant of China Pharmaceutical University 20180815
Corresponding Author Harvest F Gu, Laboratory of Molecular Medicine, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, No. 24 Tongjia Alley, Gulou District, Nanjing 210009, Jiangsu Province, China. feng.gu@cpu.edu.cn
Key Words Diabetic kidney disease; DNA methylation; Solute carrier family 30 member 8; Type 2 diabetes; Hypermethylation
Core Tip Solute carrier family 30 member 8 (SLC30A8) is a β-cell specific Zn transporter in insulin secretory granules. DNA in the SLC30A8 gene promoter region is hypermethylated. SLC30A8 promoter hypermethylation is associated with both type 2 diabetes and diabetic kidney disease. This study aims to evaluate whether DNA methylation changes in SLC30A8 is associated with type 2 diabetes and diabetic kidney disease.
Publish Date 2026-03-12 09:18
Citation

Li N, Li YP, Xu Q, Xu J, Yu YH, Su J, Shen C, Yu JY, Gu HF. SLC30A8 promoter hypermethylation is associated with type 2 diabetes and diabetic kidney disease in a Chinese population. World J Diabetes 2026; 17(3): 113947

URL https://www.wjgnet.com/1948-9358/full/v17/i3/113947.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i3.113947
Full Article (PDF) WJD-17-113947-with-cover.pdf
The ARRIVE Guidelines 113947-The-ARRIVE-Guidelines.pdf
Manuscript File 113947_Auto_Edited_025745.docx
Answering Reviewers 113947-answering-reviewers.pdf
Audio Core Tip 113947-audio.m4a
Biostatistics Review Certificate 113947-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 113947-conflict-of-interest-statement.pdf
Copyright License Agreement 113947-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 113947-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document 113947-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 113947-non-native-speakers.pdf
Supplementary Material 113947-supplementary-material.pdf
Peer-review Report 113947-peer-reviews.pdf
Journal Editor-in-Chief Review Report 113947-journal-editor-in-chief.pdf
Scientific Misconduct Check 113947-scientific-misconduct-check.png
Scientific Editor Work List 113947-scientific-editor-work-list.pdf
CrossCheck Report 113947-crosscheck-report.pdf