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3/14/2026 5:02:39 AM | Browse: 14 | Download: 19
Publication Name World Journal of Nephrology
Manuscript ID 114165
Country India
Received
2025-09-15 07:29
Peer-Review Started
2025-09-15 07:29
First Decision by Editorial Office Director
2025-09-23 09:36
Return for Revision
2025-09-23 09:36
Revised
2025-10-02 22:31
Publication Fee Transferred
Second Decision by Editor
2025-12-16 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-16 11:47
Articles in Press
2025-12-16 11:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-28 03:33
Publish the Manuscript Online
2026-03-14 04:49
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Prospective Study
Article Title Dual-score framework: National Early Warning Score 2 and quick Sequential Organ Failure Assessment scores in acute pyelonephritis
Manuscript Source Invited Manuscript
All Author List Punith R Jain, Suryaram Aravind, Prajeeth Reddy K, Manikantan Shekar, Velmurugan Palaniyandi, Hariharasudhan Sekar and Sriram Krishnamoorthy
Funding Agency and Grant Number
Corresponding Author Sriram Krishnamoorthy, Head, Professor, Department of Urology and Renal Transplantation, Sri Ramachandra Institute of Higher Education and Research, No. 1 Ramachandra Nagar, Porur, Chennai 600116, Tamil Nadu, India. sriram.k@sriramachandra.edu.in
Key Words Acute pyelonephritis; Triage; Intervention; In-hospital mortality; quick Sequential Organ Failure Assessment; National Early Warning Score 2; Early warning scores
Core Tip Acute pyelonephritis (APN) is common in urology, but existing studies on early warning scores often mix heterogeneous sepsis cohorts or emphasize stone-related or emphysematous pyelonephritis. Our prospective study is the first to focus exclusively on non-obstructive, non-emphysematous APN, a group frequently overlooked yet clinically challenging. We demonstrate that the National Early Warning Score 2 score reliably identifies patients who require intensive care unit care or urgent intervention, while the quick Sequential Organ Failure Assessment score more accurately predicts mortality. Used together, they provide a complementary dual-score framework for bedside triage and prognostication. This simple approach offers urologists and nephrologists a practical, objective tool to enhance decision-making and improve patient outcomes.
Publish Date 2026-03-14 04:49
Citation

Jain PR, Aravind S, K PR, Shekar M, Palaniyandi V, Sekar H, Krishnamoorthy S. Dual-score framework: National Early Warning Score 2 and quick Sequential Organ Failure Assessment scores in acute pyelonephritis. World J Nephrol 2026; 15(1): 114165

URL https://www.wjgnet.com/2220-6124/full/v15/i1/114165.htm
DOI https://dx.doi.org/10.5527/wjn.v15.i1.114165
Full Article (PDF) WJN-15-114165-with-cover.pdf
CONSORT 2010 Statement 114165-CONSORT-2010-statement.pdf
Manuscript File 114165_Auto_Edited_060446.docx
Answering Reviewers 114165-answering-reviewers.pdf
Audio Core Tip 114165-audio.m4a
Biostatistics Review Certificate 114165-biostatistics-statement.pdf
Clinical Trial Registration Statement 114165-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 114165-conflict-of-interest-statement.pdf
Copyright License Agreement 114165-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 114165-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 114165-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 114165-non-native-speakers.pdf
Peer-review Report 114165-peer-reviews.pdf
Scientific Misconduct Check 114165-scientific-misconduct-check.png
Scientific Editor Work List 114165-scientific-editor-work-list.pdf
CrossCheck Report 114165-crosscheck-report.pdf