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3/14/2026 5:02:39 AM | Browse: 78 | Download: 132
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Received |
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2025-09-15 07:12 |
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Peer-Review Started |
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2025-09-15 07:12 |
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First Decision by Editorial Office Director |
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2025-09-29 08:49 |
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Return for Revision |
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2025-09-29 08:49 |
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Revised |
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2025-10-25 08:27 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-07 02:41 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-07 09:59 |
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Articles in Press |
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2026-01-07 09:59 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-10 09:32 |
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Publish the Manuscript Online |
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2026-03-14 04:49 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Minireviews |
| Article Title |
Immune checkpoint inhibitor-related acute kidney injury: A diagnostic and therapeutic challenge for nephrologists
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Muhammad M Javaid, Gina Tonkin-Hill and Martin Klein |
| Funding Agency and Grant Number |
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| Corresponding Author |
Muhammad M Javaid, Adjunct Associate Professor, Affiliate Associate Professor, Consultant, FASN, FRACP, FRCP, Department of Medicine, South West Healthcare, 25 Ryot Street, Warrnambool 3280, Victoria, Australia. mmjavaid@doctors.org.uk |
| Key Words |
Acute kidney injury; Acute tubulointerstitial nephritis; Immune checkpoint inhibitors; Glomerulonephritis; Nephritis; Nephrotoxicity |
| Core Tip |
Immune-mediated acute kidney injury is rare in cancer patients treated with immune checkpoint inhibitors. The presenting features are non-specific, making it difficult to distinguish from other more commonly encountered pre-renal and post-renal causes. However, a precise diagnosis is imperative for instigating appropriate management plan. Attention to the presence of risk factors and other associated features can guide further investigations. Confirmation of diagnosis with a kidney biopsy can minimise the risk of inappropriate exposure to immunosuppression in already seriously unwell patient. |
| Publish Date |
2026-03-14 04:49 |
| Citation |
Javaid MM, Tonkin-Hill G, Klein M. Immune checkpoint inhibitor-related acute kidney injury: A diagnostic and therapeutic challenge for nephrologists. World J Nephrol 2026; 15(1): 114239 |
| URL |
https://www.wjgnet.com/2220-6124/full/v15/i1/114239.htm |
| DOI |
https://dx.doi.org/10.5527/wjn.v15.i1.114239 |
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