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Publication Name World Journal of Orthopedics
Manuscript ID 114482
Country China
Received
2025-09-22 03:02
Peer-Review Started
2025-09-22 03:02
First Decision by Editorial Office Director
2025-10-18 02:17
Return for Revision
2025-10-18 02:17
Revised
2025-10-21 10:58
Publication Fee Transferred
2025-10-22 09:34
Second Decision by Editor
2025-12-01 02:58
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-01 05:53
Articles in Press
2025-12-01 05:53
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-05 08:49
Publish the Manuscript Online
2026-01-09 09:47
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Systematic Reviews
Article Title Factors associated with aseptic loosening after primary total hip arthroplasty: A systematic review and meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Guo-Qing Li, Ji Zhang and Yong Huang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82402789
Beijing Jishuitan Hospital Youcai Plan KYYC202402
Beijing Jishuitan Research Funding HL202402
Beijing Natural Science Foundation L232062, L222063
Corresponding Author Guo-Qing Li, MD, Principal Investigator, Senior Scientist, Department of Orthopedics, Beijing Jishuitan Hospital, Capital Medical University, No. 31 Xinjiekou East Street, Xicheng District, Beijing 100035, China. guoqingli@pku.edu.cn
Key Words Factors; Aseptic loosening; Primary total hip arthroplasty; Systematic review; Meta-analysis
Core Tip Aseptic loosening is the main cause of failure in primary total hip arthroplasty, yet the key risk factors remain unclear. Our meta-analysis of 20 studies clarifies this: Modifiable factors like high body mass index, comorbidity burden, and prosthesis choice significantly increase risk, while surgical expertise is protective. This evidence enables surgeons to identify high-risk patients and prioritize modifiable factors, paving the way for personalized prevention strategies and improved implant longevity.
Publish Date 2026-01-09 09:47
Citation

Li GQ, Zhang J, Huang Y. Factors associated with aseptic loosening after primary total hip arthroplasty: A systematic review and meta-analysis. World J Orthop 2026; 17(1): 114482

URL https://www.wjgnet.com/2218-5836/full/v17/i1/114482.htm
DOI https://dx.doi.org/10.5312/wjo.v17.i1.114482
Full Article (PDF) WJO-17-114482-with-cover.pdf
PRISMA 2009 Checklist 114482-PRISMA-2009-Checklist.pdf
Manuscript File 114482_Auto_Edited_074031.docx
Answering Reviewers 114482-answering-reviewers.pdf
Audio Core Tip 114482-audio.m4a
Biostatistics Review Certificate 114482-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 114482-conflict-of-interest-statement.pdf
Copyright License Agreement 114482-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 114482-non-native-speakers.pdf
Supplementary Material 114482-supplementary-material.pdf
Peer-review Report 114482-peer-reviews.pdf
Scientific Misconduct Check 114482-scientific-misconduct-check.png
Scientific Editor Work List 114482-scientific-editor-work-list.pdf
CrossCheck Report 114482-crosscheck-report.pdf