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3/12/2026 9:33:49 AM | Browse: 9 | Download: 4
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2025-10-09 00:15 |
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2026-03-12 09:18 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Editorial |
| Article Title |
Molecular insights into hyperglycemia-associated coronary heart disease: From glycemic variability and heart rate dynamics to long noncoding RNAs
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Shilpy Singh, Varun Kumar Sharma and Dharmsheel Shrivastav |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dharmsheel Shrivastav, Assistant Professor, PhD, Department of Biotechnology, Microbiology and Forensic Sciences, School of Sciences, Noida International University, Plot 1, Yamuna Expy, Sector 17A, Greater Noida 203201, Uttar Pradesh, India. dharmsheel.shrivastav1@gmail.com |
| Key Words |
Long non-coding RNA; Transcription factor; Diabetes mellitus; Coronary artery disease; Glycemic variability |
| Core Tip |
The retrospective study by Li et al highlights the interplay between glycemic variability and heart rate dynamics in elderly patients with type 2 diabetes and coronary heart disease. It demonstrates that combining glucose excursion markers surpasses traditional heart rate variability indices in predicting myocardial ischemia. Emerging evidence implicates lncRNA PSMB8-AS-1 and transcription factor triads (PSMB9/ZEB-1/NONO) in linking inflammation and vascular instability to acute coronary syndromes. These findings support integrating dynamic glucose monitoring with molecular biomarker profiling to enhance precision cardiovascular risk stratification in diabetic patients. |
| Publish Date |
2026-03-12 09:18 |
| Citation |
Singh S, Sharma VK, Shrivastav D. Molecular insights into hyperglycemia-associated coronary heart disease: From glycemic variability and heart rate dynamics to long noncoding RNAs. World J Diabetes 2026; 17(3): 115033 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i3/115033.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i3.115033 |
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