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2/12/2026 11:23:28 AM | Browse: 3 | Download: 13
Publication Name World Journal of Hepatology
Manuscript ID 115063
Country Indonesia
Received
2025-10-13 08:08
Peer-Review Started
2025-10-13 08:08
First Decision by Editorial Office Director
2025-10-29 08:32
Return for Revision
2025-10-29 08:32
Revised
2025-11-12 02:43
Publication Fee Transferred
2025-11-18 12:17
Second Decision by Editor
2025-12-16 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-12-16 07:15
Articles in Press
2025-12-16 07:15
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-04 00:41
Publish the Manuscript Online
2026-02-12 11:20
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Diagnostic challenges of clinically significant portal hypertension in geriatric metabolic dysfunction-associated fatty liver disease: A case report
Manuscript Source Unsolicited Manuscript
All Author List Femmy Nurul Akbar, Nikko Darnindro, Annisa Ayu Wardhani, Safira Rosiana Choirida, Shafa Nada Saphira, Griffith Ismed, Ida Ayu Made Kshanti, Syifa Mustika and Hari Hendarto
Funding Agency and Grant Number
Corresponding Author Femmy Nurul Akbar, Associate Professor, Department of Internal Medicine, Faculty of Medicine, Universitas Islam Negeri Syarif Hidayatullah Jakarta, Ir H. Juanda Street No.95, Ciputat District, South Tangerang 15412, Banten, Indonesia. femmy.nurul@uinjkt.ac.id
Key Words Metabolically-dysfunction-associated fatty liver disease; Liver cirrhosis; Clinically significant portal hypertension; Hepatic fibrosis assessment; Geriatric patients; Case report
Core Tip Metabolic dysfunction-associated fatty liver disease (MAFLD) is a chronic condition characterized by excess fat accumulation in the liver along with at least one cardiometabolic risk factor. MAFLD can progress silently to liver cirrhosis, often without noticeable symptoms, until clinically significant portal hypertension (CSPH) develops. CSPH can develop early in MAFLD, even before advanced hepatic fibrosis or cirrhosis sets in. We reported a case of a geriatric patient with MAFLD who had CSPH. Following variceal ligation and medical treatment, the patient showed notable improvement. However, diagnosing such cases in daily clinical practice remains quite challenging.
Publish Date 2026-02-12 11:20
Citation

Akbar FN, Darnindro N, Wardhani AA, Choirida SR, Saphira SN, Ismed G, Kshanti IAM, Mustika S, Hendarto H. Diagnostic challenges of clinically significant portal hypertension in geriatric metabolic dysfunction-associated fatty liver disease: A case report. World J Hepatol 2026; 18(2): 115063

URL https://www.wjgnet.com/1948-5182/full/v18/i2/115063.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i2.115063
Full Article (PDF) WJH-18-115063-with-cover.pdf
CARE Checklist–2016 115063-CARE-Checklist-2016.pdf
Manuscript File 115063_Auto_Edited_061023.docx
Answering Reviewers 115063-answering-reviewers.pdf
Audio Core Tip 115063-audio.m4a
Conflict-of-Interest Disclosure Form 115063-conflict-of-interest-statement.pdf
Copyright License Agreement 115063-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 115063-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 115063-non-native-speakers.pdf
Peer-review Report 115063-peer-reviews.pdf
Scientific Misconduct Check 115063-scientific-misconduct-check.png
Scientific Editor Work List 115063-scientific-editor-work-list.pdf
CrossCheck Report 115063-crosscheck-report.pdf