Publication Name	World Journal of Hematology
Manuscript ID	11564
Country	Argentina

Received	2014-05-28 11:27
Peer-Review Started	2014-05-28 17:21
To Make the First Decision	2014-06-27 11:53
Return for Revision	2014-06-27 18:27
Revised	2014-07-12 07:16
Second Decision	2014-09-19 11:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-09-19 11:10
Articles in Press	2014-09-19 11:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-04 16:47
Publish the Manuscript Online	2014-11-14 13:04

ISSN	2218-6204 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Review
Article Title	Follicular helper T lymphocytes in health and disease
Manuscript Source	Invited Manuscript
All Author List	Cecilia Parodi, María Noel Badano, Nora Galassi, Ana Coraglia, Patricia Baré, Alejandro Malbrán and María Marta de Elizalde de Bracco
Funding Agency and Grant Number	Funding Agency Grant Number Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET, PIP 0032 Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET, PIP 11220120100619CO
Corresponding Author	María Marta de Elizalde de Bracco, PhD, Chief, Department of Immunology, Instituto de Medicina Experimental (IMEX)-CONICET, Academia Nacional de Medicina (ANM), Pacheco de Melo 3081, Ciudad Autónoma de Buenos Aires 1425, Argentina. mebracco@hematologia.anm.edu.ar
Key Words	Follicular helper T (TFH) lymphocytes; TFH development; Chemokine (C-X-C motif) receptor 5; Interleukin-21; Programmed cell death-1/Programmed cell death ligand 1 (PDL-1) or PDL-2; Primary immunodeficiencies; Autoimmunity; Chronic viral infections; Protozoan infections
Core Tip	Follicular helper T lymphocytes (TFH) are essential to establish a correct and protective humoral immune response. Correct regulation of their development and differentiation is necessary to achieve a normal antibody response. They can be characterized by their phenotype and function. It has been proposed that their role is important in the generation of immunodeficiency or autoimmunity, as well as in the control of chronic viral or protozoan infections. This review comments recent advances in human TFH research that may be useful in order to design adequate therapeutic or vaccination strategies.
Publish Date	2014-11-14 13:04
Citation	Parodi C, Badano MN, Galassi N, Coraglia A, Baré P, Malbrán A, de Elizalde de Bracco MM. Follicular helper T lymphocytes in health and disease. World J Hematol 2014; 3(4): 118-127
URL	http://www.wjgnet.com/2218-6204/full/v3/i4/118.htm
DOI	http://dx.doi.org/10.5315/wjh.v3.i4.118

Full Article (PDF)	WJH-3-118.pdf
Full Article (Word)	WJH-3-118.doc
Manuscript File	11564-Review.doc
Answering Reviewers	11564-Answering reviewers.pdf
Copyright License Agreement	11564-Copyright assignment.pdf
Peer-review Report	11564-Peer review(s).pdf
Scientific Misconduct Check	11564-CrossCheck.jpg
Scientific Editor Work List	11564-Scientific editor work list.pdf