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1/15/2026 7:19:47 AM | Browse: 106 | Download: 292
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Received |
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2025-10-24 06:28 |
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Peer-Review Started |
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2025-10-24 06:28 |
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First Decision by Editorial Office Director |
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2025-11-18 10:36 |
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2025-11-18 10:36 |
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Revised |
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2025-11-19 13:53 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-12-25 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-12-25 06:22 |
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Articles in Press |
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2025-12-25 06:22 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-01-12 10:57 |
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Publish the Manuscript Online |
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2026-01-15 03:16 |
| ISSN |
2218-6220 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Obstetrics & Gynecology |
| Manuscript Type |
Case Report |
| Article Title |
Cryptococcal antigenemia during pregnancy: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Maureen Mueni Mark, Allan Kariuki Ng’ang’a, Felix Pius Omullo, Gudisa Bereda and Charles Tung’ani Muchiri |
| Funding Agency and Grant Number |
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| Corresponding Author |
Felix Pius Omullo, MD, Senior Researcher, Department of Medical Services, Equity Afya, Kanaamkemer, Lodwar 399-30500, Turkana, Kenya. piuskirasia@gmail.com |
| Key Words |
Cryptococcal antigenemia; Human immunodeficiency virus; Pregnancy; Fluconazole; Antiretroviral therapy; Immune reconstitution inflammatory syndrome; Perinatal transmission; Case report |
| Core Tip |
This case illustrates a high-stakes clinical dilemma in late pregnancy: Adhering to the standard 4-6 week antiretroviral therapy (ART) delay to prevent immune reconstitution inflammatory syndrome (IRIS) vs aggressively suppressing the human immunodeficiency virus viral load to prevent perinatal transmission. We demonstrate that for a woman presenting in the third trimester with isolated antigenemia, a truncated ART delay-supported by preemptive high-dose fluconazole and vigilant monitoring-was a calculated risk that achieved viral suppression for delivery without provoking IRIS. This case argues not for a new guideline, but for nuanced, individualized decision-making in complex scenarios, highlighting a critical evidence gap and the need to better define IRIS risk in pregnant women with antigenemia. |
| Publish Date |
2026-01-15 03:16 |
| Citation |
Mark MM, Ng’ang’a AK, Omullo FP, Bereda G, Muchiri CT. Cryptococcal antigenemia during pregnancy: A case report. World J Obstet Gynecol 2026; 15(1): 115708 |
| URL |
https://www.wjgnet.com/2218-6220/full/v15/i1/115708.htm |
| DOI |
https://dx.doi.org/10.5317/wjog.v15.i1.115708 |
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