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2/10/2026 6:14:53 AM | Browse: 97 | Download: 164
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2025-10-27 07:39 |
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2025-10-27 07:40 |
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2026-01-08 03:49 |
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2026-01-08 03:49 |
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2026-01-15 15:34 |
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2026-02-04 02:40 |
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2026-02-04 07:18 |
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Articles in Press |
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2026-02-04 07:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-02-06 02:02 |
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Publish the Manuscript Online |
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2026-02-10 06:02 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Human leukocyte antigen variants and clinical features of primary biliary cholangitis: Cumulative contributions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Abdellatif Bouayad |
| Funding Agency and Grant Number |
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| Corresponding Author |
Abdellatif Bouayad, Associate Professor, MD, Department of Immunology, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, 4867 Oujda l’Université, Oujda 60049, Morocco. a.bouayad@ump.ac.ma |
| Key Words |
Human leukocyte antigen class II; Human leukocyte antigen-G; Primary biliary cholangitis; Prognosis; Primary biliary cholangitis-autoimmune hepatitis overlap syndrome; Therapy response |
| Core Tip |
Specific classical human leukocyte antigen (HLA) alleles and haplotypes may influence predisposition to primary biliary cholangitis (PBC), prognosis, and the development of PBC-autoimmune hepatitis overlap syndrome. Potential cumulative contributions between the non-classical HLA-G*01: 01: 01: 08-UTR-1 haplotype and its soluble HLA-G molecules may predict a poor therapeutic response to ursodeoxycholic acid. Thus, soluble HLA-G molecules may serve as novel, non-invasive biomarkers to guide personalized PBC treatment. |
| Publish Date |
2026-02-10 06:02 |
| Citation |
Bouayad A. Human leukocyte antigen variants and clinical features of primary biliary cholangitis: Cumulative contributions. World J Clin Cases 2026; 12(5): 115814 |
| URL |
https://www.wjgnet.com/2307-8960/full/v14/i5/115814.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v14.i5.115814 |
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