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6/11/2026 11:28:47 AM | Browse: 1 | Download: 0
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2025-10-27 01:40 |
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2025-11-18 09:39 |
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2026-01-08 02:47 |
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Typeset the Manuscript |
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2026-06-03 12:11 |
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2026-06-11 11:23 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Opinion Review |
| Article Title |
Glycated hemoglobin and cardiovascular risk in diabetes mellitus: Evolving evidence beyond glycemic control
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Manjeet Kumar Goyal, Juniali Hatwal, Rupak Desai, Tanisha Sehgal and Akash Batta |
| Funding Agency and Grant Number |
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| Corresponding Author |
Akash Batta, Assistant Professor, DM, MD, Department of Cardiology, Dayanand Medical College and Hospital, Tagore Nagar, Civil Lines, Ludhiana 141001, Punjab, India. akashbatta02@gmail.com |
| Key Words |
Glycated hemoglobin; Cardiovascular disease; Diabetes mellitus; Glycemic variability; Cardiovascular risk |
| Core Tip |
Glycated hemoglobin (HbA1c) is a well-established marker of chronic glycemia and a predictor of cardiovascular risk in diabetes, yet its role as a therapeutic target for reducing cardiovascular events is increasingly nuanced. Evidence from landmark trials highlights both the benefits of early glycemic control and the limitations of intensive HbA1c reduction in advanced disease. Glycemic variability and emerging cardioprotective therapies further challenge HbA1c-centric paradigms. Clinicians should interpret HbA1c within a broader cardiometabolic framework, integrating patient-specific factors and adjunctive risk modifiers to optimize outcomes. A shift from glucose-centric to outcome-driven strategies is essential for contemporary diabetes care. |
| Publish Date |
2026-06-11 11:23 |
| Citation |
Goyal MK, Hatwal J, Desai R, Sehgal T, Batta A. Glycated hemoglobin and cardiovascular risk in diabetes mellitus: Evolving evidence beyond glycemic control. World J Diabetes 2026; 17(6): 115820
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i6/115820.htm |
| DOI |
https://doi.org/10.4239/wjd.115820 |
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