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5/25/2026 9:59:11 AM | Browse: 6 | Download: 0
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Received |
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2025-11-02 11:41 |
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Peer-Review Started |
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2025-11-02 11:41 |
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First Decision by Editorial Office Director |
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2025-11-28 07:46 |
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Return for Revision |
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2025-11-28 07:46 |
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Revised |
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2025-12-12 02:38 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-01-30 02:29 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-01-30 07:42 |
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Articles in Press |
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2026-01-30 07:42 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-13 01:05 |
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Publish the Manuscript Online |
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2026-05-25 07:47 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Editorial |
| Article Title |
Hypoxia-inducible factor-1α/β-catenin axis: A conserved regulatory hub for enhancing stem cell function in tissue regeneration
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hui-Fang Wang, Peng-Yu Yan, Shoaib Muhammad, Yu-Xiang Liu and Chun Liu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Research Project of Basic Research Program in Shanxi Province |
202203021221268 |
| National Natural Science Foundation of China |
82305030 |
| Special Fund from Medicinal Basic Research Innovation Center of Chronic Kidney Disease, Ministry of Education, Shanxi Medical University |
CKD/SXMU-2024-04 |
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| Corresponding Author |
Chun Liu, Chief Physician, Consultant, Dean, Professor, Department of Urology, First Hospital of Shanxi Medical University, No. 85 Jiefang South Road, Taiyuan 030001, Shanxi Province, China. sxtyliuchun@126.com |
| Key Words |
Hypoxia-inducible factor-1α; β-catenin; Stem cell; Tissue regeneration; Conserved regulatory hub |
| Core Tip |
The hypoxia-inducible factor-1α/β-catenin axis functions as a conserved regulatory hub that enhances stem cell survival and angiogenic capacity under hypoxic conditions. This unidirectional signaling pathway, with hypoxia-inducible factor-1α as the upstream driver, coordinates anti-apoptotic and pro-angiogenic responses in stem cells, offering a promising target for improving cell-based therapies in ischemic diseases such as myocardial infarction. |
| Publish Date |
2026-05-25 07:47 |
| Citation |
Wang HF, Yan PY, Muhammad S, Liu YX, Liu C. Hypoxia-inducible factor-1α/β-catenin axis: A conserved regulatory hub for enhancing stem cell function in tissue regeneration. World J Stem Cells 2026; 18(5): 116050 |
| URL |
https://www.wjgnet.com/1948-0210/full/v18/i5/116050.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v18.i5.116050 |
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