Publication Name	World Journal of Gastroenterology
Manuscript ID	11627
Country	Italy

Received	2014-05-28 21:18
Peer-Review Started	2014-05-29 00:29
To Make the First Decision	2014-07-09 12:10
Return for Revision	2014-07-17 15:17
Revised	2014-08-08 06:03
Second Decision	2014-09-30 09:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-09-30 10:08
Articles in Press	2014-09-30 10:52
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-10-04 04:33
Typeset the Manuscript	2014-11-15 18:16
Publish the Manuscript Online	2014-12-02 10:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease
Manuscript Source	Invited Manuscript
All Author List	Sara Ceccarelli, Valerio Nobili and Anna Alisi
Funding Agency and Grant Number	Funding Agency Grant Number Associazione Italiana per la Ricerca sul Cancro (AIRC) MFAG 12936 (to Anna Alisi)
Corresponding Author	Anna Alisi, PhD, Hepato-Metabolic Disease Unit and Liver Research Unit, Bambino Gesù Children’s Hospital, IRCCS, S. Onofrio Square 4, 00165 Rome, Italy. anna.alisi@opbg.net
Key Words	Alcoholic liver disease; Toll-like receptors; Inflammation; Cirrhosis; Nuclear factor-B; Cytokines
Core Tip	Alcoholic liver disease (ALD) pathogenesis is quite complex and requires the activation/inhibition of several molecular pathways. The inflammatory storm caused by alcohol abuse on the gut-liver axis and consequent activation of Toll-like receptor (TLR) signaling is topical for researchers and physicians, both for understanding ALD pathophysiology and for translating novel clues into clinical practice. Here, we focus on the current evidence of TLR involvement in inflammation during ALD in experimental models and humans, offering readers with no first-hand knowledge of this topic a valuable tool to start novel studies.
Publish Date	2014-12-02 10:46
Citation	Ceccarelli S, Nobili V, Alisi A. Toll-like receptor-mediated signaling cascade as a regulator of the inflammation network during alcoholic liver disease. World J Gastroenterol 2014; 20(44): 16443-16451
URL	http://www.wjgnet.com/1007-9327/full/v20/i44/16443.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i44.16443

Full Article (PDF)	WJG-20-16443.pdf
Full Article (Word)	WJG-20-16443.doc
Manuscript File	11627-Review.doc
Answering Reviewers	11627-Answering reviewers.pdf
Copyright License Agreement	11627-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	11627-Language certificate.pdf
Peer-review Report	11627-Peer review(s).pdf
Scientific Misconduct Check	11627-CrossCheck.jpg
Scientific Editor Work List	11627-Scientific editor work list.pdf