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3/16/2026 8:30:47 AM | Browse: 26 | Download: 20
Publication Name World Journal of Gastroenterology
Manuscript ID 116289
Country China
Received
2025-11-07 08:09
Peer-Review Started
2025-11-07 08:09
First Decision by Editorial Office Director
2025-12-04 09:25
Return for Revision
2025-12-04 09:25
Revised
2025-12-06 12:55
Publication Fee Transferred
Second Decision by Editor
2026-01-05 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-01-06 01:09
Articles in Press
2026-01-06 01:09
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-02-25 09:02
Publish the Manuscript Online
2026-03-16 08:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Letter to the Editor
Article Title Should repeat ablation be viewed as strategic rather than salvage in refractory colorectal cancer liver metastasis?
Manuscript Source Invited Manuscript
All Author List Sen Li and Zhi-Chun Wang
Funding Agency and Grant Number
Corresponding Author Zhi-Chun Wang, Associate Chief Physician, MD, General Surgery Breast Diagnosis and Treatment Center, Jiujiang City Key Laboratory of Cell Therapy, JiuJiang No. 1 People’s Hospital, No. 48 Taling South Road, Jiujiang 341000, Jiangxi Province, China. mikeauthor@qq.com
Key Words Colorectal liver metastases; Radiofrequency ablation; Repeat ablation; Locoregional therapy; Tumor microenvironment; Liver functional reserve; Hepatic tumor burden; Thermal injury mechanism; Long-term disease control; Treatment sequencing
Core Tip Repeated radiofrequency ablation in patients with chemotherapy-refractory colorectal liver metastases can no longer be viewed solely as a salvage procedure. When guided by radiologic evidence of viable tumor enhancement and applied in a staged manner, repeat ablation may function as an active, strategy-driven modality for sustained disease control. By integrating tumor size, hepatic reserve, and absence of uncontrolled extrahepatic spread into candidate selection, repeat ablation can serve as a bridge to resection or transplantation, a consolidation method after partial systemic response, or a long-term approach to maintain quality of life.
Publish Date 2026-03-16 08:22
Citation

Li S, Wang ZC. Should repeat ablation be viewed as strategic rather than salvage in refractory colorectal cancer liver metastasis? World J Gastroenterol 2026; 32(11): 116289

URL https://www.wjgnet.com/1007-9327/full/v32/i11/116289.htm
DOI https://dx.doi.org/10.3748/wjg.v32.i11.116289
Full Article (PDF) WJG-32-116289-with-cover.pdf
Manuscript File 116289_Auto_Edited_072343.docx
Answering Reviewers 116289-answering-reviewers.pdf
Audio Core Tip 116289-audio.mp3
Conflict-of-Interest Disclosure Form 116289-conflict-of-interest-statement.pdf
Copyright License Agreement 116289-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 116289-non-native-speakers.pdf
Peer-review Report 116289-peer-reviews.pdf
Scientific Misconduct Check 116289-scientific-misconduct-check.png
Scientific Editor Work List 116289-scientific-editor-work-list.pdf
CrossCheck Report 116289-crosscheck-report.pdf