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6/11/2026 11:28:47 AM | Browse: 2 | Download: 7
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Received |
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2025-11-12 02:09 |
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2025-11-12 05:45 |
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2025-12-11 08:13 |
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2025-12-11 08:13 |
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2025-12-12 18:50 |
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Second Decision by Editor |
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2026-01-12 02:45 |
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Final Decision by Editorial Office Director |
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2026-01-12 09:21 |
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Articles in Press |
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2026-01-12 09:21 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-03 12:06 |
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Publish the Manuscript Online |
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2026-06-11 11:23 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Editorial |
| Article Title |
Glucagon-like peptide-1 receptor agonists in type 2 diabetes: Evidence for disease modification and therapeutic switching
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Vanishri Ganakumar, Cornelius J Fernandez and Joseph M Pappachan |
| Funding Agency and Grant Number |
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| Corresponding Author |
Joseph M Pappachan, FRCP, MD, MRCP, Professor, Senior Researcher, Faculty of Science, Manchester Metropolitan University, All Saints Building, Oxford Road, Manchester M15 6BH, Greater Manchester, United Kingdom. drpappachan@yahoo.co.in |
| Key Words |
Glucagon-like peptide-1 receptor agonists; Incretin polyagonists; Type 2 diabetes mellitus; Switching glucagon-like peptide-1 receptor agonist; Glycemic control |
| Core Tip |
Pharmacological manipulation of the incretin system has revolutionised the management of type 2 diabetes mellitus (T2DM) in the 21st century. The first few drug molecules in this group were the glucagon-like peptide-1 receptor agonists (GLP-1RA), which have been used for treating patients with T2DM in the past 2 decades. Newer molecules, including incretin polyagonists, with longer half-lives and dosing intervals, and better cardiometabolic outcomes, are being added recently. A study by Kassem et al published in the World Journal of Diabetes provides us with robust evidence from a large real-world study from Israel on the benefits of switching from an old GLP-1RA to a newer agent, the theme of this editorial. |
| Publish Date |
2026-06-11 11:23 |
| Citation |
Ganakumar V, Fernandez CJ, Pappachan JM. Glucagon-like peptide-1 receptor agonists in type 2 diabetes: Evidence for disease modification and therapeutic switching. World J Diabetes 2026; 17(6): 116477
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i6/116477.htm |
| DOI |
https://doi.org/10.4239/wjd.116477 |
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