| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Comparison of triglyceride-glucose index and its derived indices as markers for adverse pregnancy outcomes
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Shu-Yu Li, Mei-Mei Hu, Lan-Lan Xiang, Yi-Tian Zhu, Yun Liu, Yi-Ting Chen, Ya-Jun Chen, Yu Zeng and Tian-Ying Zhong |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Nanjing Medical Science and Technique Development Foundation |
YKK23151 |
| the Opening Foundation of Key Laboratory |
JSHD202313 |
| Yingke Xinchuang Research Foundation of Jiangsu Blood Transfusion Association |
JSYK2024006 |
| Open Project of the State Key Laboratory of Reproductive Medicine of Nanjing Medical University |
SKLRM-K202107 |
|
| Corresponding Author |
Tian-Ying Zhong, Professor, Department of Clinical Laboratory, Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital, No. 123 Tianfei Alley, Mochou Road, Nanjing 210002, Jiangsu Province, China. zhongtianying@njmu.edu.cn |
| Key Words |
Triglyceride-glucose index; Derived triglyceride-glucose indices; Insulin resistance; Maternal obesity; Adverse pregnancy outcomes |
| Core Tip |
This study demonstrates that integrating obesity metrics with the triglyceride-glucose (TyG) index significantly enhances the prediction of adverse pregnancy outcomes. The derived indices, particularly TyG-body mass index (TyG-BMI), showed superior predictive performance for hypertensive disorders of pregnancy, cesarean delivery, and large-for-gestational-age infants compared to the TyG index alone. These findings highlight that simple, cost-effective composite indices like TyG-BMI can serve as useful tools for early identification of high-risk pregnancies, offering significant clinical value. |
| Publish Date |
2026-05-11 09:00 |
| Citation |
Li SY, Hu MM, Xiang LL, Zhu YT, Liu Y, Chen YT, Chen YJ, Zeng Y, Zhong TY. Comparison of triglyceride-glucose index and its derived indices as markers for adverse pregnancy outcomes. World J Diabetes 2026; 17(5): 117022 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i5/117022.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i5.117022 |
