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3/26/2026 9:24:47 AM | Browse: 20 | Download: 14
Publication Name World Journal of Hepatology
Manuscript ID 117367
Country Colombia
Received
2025-12-08 00:42
Peer-Review Started
2025-12-08 00:42
First Decision by Editorial Office Director
2026-01-14 08:07
Return for Revision
2026-01-14 08:07
Revised
2026-01-27 04:03
Publication Fee Transferred
Second Decision by Editor
2026-02-13 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-13 08:03
Articles in Press
2026-02-13 08:03
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-20 06:46
Publish the Manuscript Online
2026-03-26 09:23
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Editorial
Article Title Autoimmune liver diseases in older adults: Clinical challenges and management considerations
Manuscript Source Invited Manuscript
All Author List Pablo Guillermo Hernández-Almonacid, Juan Sebastian Espejo-Amado and Ximena Marín-Quintero
Funding Agency and Grant Number
Corresponding Author Pablo Guillermo Hernández-Almonacid, Consultant, MD, Department of Internal Medicine, National University of Colombia, Kr 35 bis 60-45 A311, Bogota 111311, Colombia. pghernandezalm@gmail.com
Key Words Autoimmune liver diseases; Autoimmune hepatitis; Primary biliary cholangitis; Primary sclerosing cholangitis; Aged; Geriatric comorbidities
Core Tip Autoimmune liver diseases are increasingly relevant in older adults, with changing epidemiology and rising incidence, including presentation peaks in this age group. Clinical manifestations range from unusual presentations, acute liver failure, and acute hepatitis to more common indolent forms with minimal symptoms. Serologic testing does not differ from younger patients, but due to comorbidities, liver biopsy remains essential. First-line treatment generally does not change and is often effective, although older adults are more vulnerable to steroid-related complications and polypharmacy. Liver transplantation remains an option. However, this population is still understudied, and future research should incorporate comprehensive geriatric assessment
Publish Date 2026-03-26 09:23
Citation

Hernández-Almonacid PG, Espejo-Amado JS, Marín-Quintero X. Autoimmune liver diseases in older adults: Clinical challenges and management considerations. World J Hepatol 2026; 18(3): 117367

URL https://www.wjgnet.com/1948-5182/full/v18/i3/117367.htm
DOI https://dx.doi.org/10.4254/wjh.v18.i3.117367
Full Article (PDF) WJH-18-117367-with-cover.pdf
Manuscript File 117367_Auto_Edited_011037.docx
Answering Reviewers 117367-answering-reviewers.pdf
Audio Core Tip 117367-audio.mp3
Conflict-of-Interest Disclosure Form 117367-conflict-of-interest-statement.pdf
Copyright License Agreement 117367-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 117367-non-native-speakers.pdf
Peer-review Report 117367-peer-reviews.pdf
Scientific Misconduct Check 117367-scientific-misconduct-check.png
Scientific Editor Work List 117367-scientific-editor-work-list.pdf
CrossCheck Report 117367-crosscheck-report.pdf