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5/11/2026 9:13:23 AM | Browse: 21 | Download: 48
Publication Name World Journal of Diabetes
Manuscript ID 117583
Country China
Received
2025-12-11 08:43
Peer-Review Started
2025-12-14 15:16
First Decision by Editorial Office Director
2026-01-09 08:02
Return for Revision
2026-01-09 08:02
Revised
2026-01-16 09:15
Publication Fee Transferred
2026-01-19 06:19
Second Decision by Editor
2026-03-03 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-10 06:04
Articles in Press
2026-03-10 06:04
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-25 11:17
Publish the Manuscript Online
2026-05-11 09:00
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Observational Study
Article Title Visceral fat area and remnant cholesterol in type 2 diabetes: Nonlinear associations and thresholds
Manuscript Source Unsolicited Manuscript
All Author List Dong-Jian Chai, Chun-Yan Zhu, Yi-Ming Zhang and Zi-Chen Rao
Funding Agency and Grant Number
Corresponding Author Zi-Chen Rao, MD, Endocrinology, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, No. 100 Minjiang Dadao, West District,, Quzhou 324000, Zhejiang Province, China. rzc1522@wmu.edu.cn
Key Words Visceral fat area; Residual cholesterol; Residual cholesterol-inflammation index; Type 2 diabetes; Non-linear dose-response
Core Tip This cross-sectional study of adults with type 2 diabetes (T2D) quantified visceral fat area (VFA) and examined its associations with residual cholesterol (RC) and the RC-inflammation index (RCII; RC/C-reactive protein). Higher VFA was independently associated with higher RC, and showed a clear non-linear pattern with a threshold at 126 cm2. RCII showed a weaker association and only a borderline threshold signal at 118 cm2, which should be interpreted as exploratory. These findings suggest that quantifying VFA may help contextualize remnant cholesterol-related burden beyond conventional lipid measures in T2D.
Publish Date 2026-05-11 09:00
Citation

Chai DJ, Zhu CY, Zhang YM, Rao ZC. Visceral fat area and remnant cholesterol in type 2 diabetes: Nonlinear associations and thresholds. World J Diabetes 2026; 17(5): 117583

URL https://www.wjgnet.com/1948-9358/full/v17/i5/117583.htm
DOI https://dx.doi.org/10.4239/wjd.v17.i5.117583
Full Article (PDF) WJD-17-117583-with-cover.pdf
STROBE Statement 117583-STROBE-statement.pdf
Manuscript File 117583_Auto_Edited_043127.docx
Answering Reviewers 117583-answering-reviewers.pdf
Audio Core Tip 117583-audio.m4a
Biostatistics Review Certificate 117583-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 117583-conflict-of-interest-statement.pdf
Copyright License Agreement 117583-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 117583-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 117583-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 117583-non-native-speakers.pdf
Peer-review Report 117583-peer-reviews.pdf
Journal Editor-in-Chief Review Report 117583-journal-editor-in-chief.pdf
Scientific Misconduct Check 117583-scientific-misconduct-check.png
Scientific Editor Work List 117583-scientific-editor-work-list.pdf
CrossCheck Report 117583-crosscheck-report.pdf