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5/13/2026 9:09:34 AM | Browse: 22 | Download: 29
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Received |
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2025-12-22 06:56 |
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Peer-Review Started |
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2025-12-22 06:56 |
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First Decision by Editorial Office Director |
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2025-12-29 09:11 |
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Return for Revision |
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2025-12-29 09:11 |
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Revised |
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2025-12-30 19:14 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-02-03 02:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-02-03 04:39 |
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Articles in Press |
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2026-02-03 04:39 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-24 02:11 |
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Publish the Manuscript Online |
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2026-05-13 08:18 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Minireviews |
| Article Title |
Neuro-ophthalmic review on pediatric myopia: Advancing from refraction to a brain-centric model of axial growth
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Matteo Capobianco, Simonetta Gaia Nicolosi, Edoardo Dammino, Francesco Cappellani, Marieme Khouyyi, Fabiana D’Esposito, Caterina Gagliano and Marco Zeppieri |
| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Zeppieri, Consultant, MD, PhD, Postdoc, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it |
| Key Words |
Myopia; Child; Axial length; Eye; Visual pathways; Retina; Neuroplasticity; Dopamine |
| Core Tip |
Pediatric myopia is not simply a refractive state, but a disorder of visually driven axial elongation shaped by neuroretinal signaling and developmental visual experience. Evidence supports prioritizing axial length as a core endpoint and integrating intermediate biomarkers (e.g., choroid and optical coherence tomography angiography or optical coherence tomography angiography metrics) to refine risk phenotyping and monitor response. A brain-informed “eye-brain axis” model can guide earlier prevention and individualized escalation, while avoiding overclaiming when central mechanisms remain only partially causal. |
| Publish Date |
2026-05-13 08:18 |
| Citation |
Capobianco M, Nicolosi SG, Dammino E, Cappellani F, Khouyyi M, D’Esposito F, Gagliano C, Zeppieri M. Neuro-ophthalmic review on pediatric myopia: Advancing from refraction to a brain-centric model of axial growth. World J Clin Pediatr 2026; 15(2): 117968 |
| URL |
https://www.wjgnet.com/2219-2808/full/v15/i2/117968.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v15.i2.117968 |
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