| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Metabolic dysfunction–associated steatotic liver disease and obstructive sleep apnea: A cohort analysis of prevalence and hepatic outcomes
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Rishi Chowdhary, Geng-Qing Song, Manjeet Kumar Goyal, Ashita Rukmini Vuthaluru, Kirti Arora, Rahul Chowdhary, Megh Patel, Akash Batta, Thai-Hau Koo, Venkata Sunkesula, Rohit Goyal and Omesh Goyal |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Manjeet Kumar Goyal, Department of Internal Medicine, Cleveland Clinic Akron General Hospital, Akron, Ohio, USA, 1, Akron General Avenue, AKron, Akron, OH 44308, United States. manjeetgoyal@gmail.com |
| Key Words |
Sleep-disordered breathing; Metabolic syndrome; TriNetX; Cirrhosis; Liver fibrosis; Intermittent hypoxia; Obstructive sleep apnea; Metabolic dysfunction-associated steatotic liver disease |
| Core Tip |
Metabolic dysfunction-associated steatotic liver disease (MASLD) and obstructive sleep apnea (OSA) often coexist due to shared risk factors. Furthermore, OSA can lead to liver complications. In this large multicenter study, patients with MASLD had a significantly higher prevalence of OSA and an earlier onset of OSA. Coexisting OSA markedly increased the long-term risk of developing hepatic fibrosis and cirrhosis. These findings highlight the importance of routine OSA screening in patients with MASLD and support integrated metabolic and sleep-focused management to prevent hepatic disease progression. |
| Publish Date |
2026-05-27 08:10 |
| Citation |
Chowdhary R, Song GQ, Goyal MK, Vuthaluru AR, Arora K, Chowdhary R, Patel M, Batta A, Koo TH, Sunkesula V, Goyal R, Goyal O. Metabolic dysfunction–associated steatotic liver disease and obstructive sleep apnea: A cohort analysis of prevalence and hepatic outcomes. World J Gastrointest Pharmacol Ther 2026; 17(2): 118130 |
| URL |
https://www.wjgnet.com/2150-5349/full/v17/i2/118130.htm |
| DOI |
https://dx.doi.org/10.4292/wjgpt.v17.i2.118130 |
