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5/6/2026 8:38:17 AM | Browse: 20 | Download: 44
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Received |
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2026-01-09 09:59 |
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2026-01-09 09:59 |
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2026-01-20 09:21 |
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2026-01-20 09:21 |
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Revised |
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2026-01-30 02:08 |
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2026-02-03 07:57 |
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2026-03-17 03:07 |
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Final Decision by Editorial Office Director |
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2026-03-17 10:17 |
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Articles in Press |
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2026-03-17 10:17 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-30 06:56 |
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Publish the Manuscript Online |
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2026-05-06 08:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Predictive value of neutrophil-lymphocyte ratio for prognosis in patients with advanced hepatocellular carcinoma treated with programmed cell death 1 inhibitors
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rui Guo and Meng Gao |
| Funding Agency and Grant Number |
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| Corresponding Author |
Rui Guo, Department of Laboratory Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, No. 7 Weiwu Road, Jinshui District, Zhengzhou 462000, Henan Province, China. guorui2460@163.com |
| Key Words |
Neutrophil-lymphocyte ratio; Hepatocellular carcinoma; Programmed cell death 1 inhibitor; Prognosis; Biomarker; Immunotherapy |
| Core Tip |
This study demonstrates that a high pretreatment neutrophil-lymphocyte ratio (NLR) is an independent predictor of poor response and survival in advanced hepatocellular carcinoma patients treated with programmed cell death 1 inhibitors. NLR reflects a systemic inflammatory state that may undermine immunotherapy efficacy. Our findings support the use of this simple, cost-effective biomarker for risk stratification and treatment personalization in the immunotherapy era. |
| Publish Date |
2026-05-06 08:34 |
| Citation |
Guo R, Gao M. Predictive value of neutrophil-lymphocyte ratio for prognosis in patients with advanced hepatocellular carcinoma treated with programmed cell death 1 inhibitors. World J Gastroenterol 2026; 32(18): 118416 |
| URL |
https://www.wjgnet.com/1007-9327/full/v32/i18/118416.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v32.i18.118416 |
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