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3/12/2026 9:31:56 AM | Browse: 70 | Download: 114
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Received |
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2026-01-20 00:52 |
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Peer-Review Started |
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2026-01-29 00:03 |
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First Decision by Editorial Office Director |
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2026-02-10 09:10 |
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Return for Revision |
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2026-02-10 09:10 |
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Revised |
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2026-02-13 14:47 |
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Publication Fee Transferred |
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2026-02-14 08:51 |
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Second Decision by Editor |
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2026-03-04 02:46 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-09 04:27 |
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Articles in Press |
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2026-03-09 04:27 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-03-09 06:21 |
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Publish the Manuscript Online |
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2026-03-12 09:18 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Review |
| Article Title |
Dysfunction of the brain-gut axis in diabetic gastroparesis: Underlying mechanisms and therapeutic strategies
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Long Jiang, Xu-Yang Hu, Hong-Xin Zheng, Ming-Hua Nan, Li-Zhe Liang, Tian-Xu Wang, Jing-Lin Li and Chang-Chuan Bai |
| Funding Agency and Grant Number |
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| Corresponding Author |
Chang-Chuan Bai, Professor, Department of Outpatient, The Second Hospital Affiliated to Liaoning University of Traditional Chinese Medicine, No. 60 Huanghebei Street, Shenyang 110034, Liaoning Province, China. bcc_clinical@163.com |
| Key Words |
Diabetic gastroparesis; Brain-gut axis; Autonomic neuropathy; Inflammation; Gut microbiota |
| Core Tip |
Diabetic gastroparesis (DGP) has traditionally been regarded as a motility disorder characterized by delayed gastric emptying. Emerging evidence indicates that DGP is a systemic disorder driven by dysfunction of the brain-gut axis, involving the central nervous system, autonomic and enteric neural networks, immune-inflammatory responses, and gut microbiota dysbiosis. This review integrates these multilevel mechanisms into a unified brain-gut axis framework and highlights therapeutic strategies targeting neural regulation, inflammation, and microbiota, providing a conceptual basis for mechanism-guided and personalized management of DGP. |
| Publish Date |
2026-03-12 09:18 |
| Citation |
Jiang WL, Hu XY, Zheng HX, Nan MH, Liang LZ, Wang TX, Li JL, Bai CC. Dysfunction of the brain-gut axis in diabetic gastroparesis: Underlying mechanisms and therapeutic strategies. World J Diabetes 2026; 17(3): 119126 |
| URL |
https://www.wjgnet.com/1948-9358/full/v17/i3/119126.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v17.i3.119126 |
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