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4/24/2026 10:26:19 AM | Browse: 17 | Download: 54
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Received |
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2026-01-27 07:03 |
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Peer-Review Started |
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2026-01-27 07:04 |
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First Decision by Editorial Office Director |
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2026-01-30 08:52 |
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Return for Revision |
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2026-01-30 08:52 |
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Revised |
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2026-02-12 02:36 |
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Publication Fee Transferred |
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2026-02-14 02:15 |
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Second Decision by Editor |
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2026-03-10 02:43 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-10 07:22 |
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Articles in Press |
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2026-03-10 07:22 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-13 02:13 |
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Publish the Manuscript Online |
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2026-04-24 10:11 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Prospective Study |
| Article Title |
Impact of oxiracetam on postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bao-Sheng Lv, Wei Wang, Mu Jin, Yan Ma, Jia-Lu Wang and Hui Gao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Hebei Province |
H2021103001 |
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| Corresponding Author |
Wei Wang, MD, Department of Neurology, Hebei Yanda Hospital, Yanjiao Development Zone, Langfang 065201, Hebei Province, China. ww19333643617@163.com |
| Key Words |
Postoperative delirium; Aged; Oxiracetam; Laparoscopic surgery; Inflammation; Randomized controlled trial |
| Core Tip |
Perioperative intravenous oxiracetam safely and effectively reduces the risk of postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery, and maintains postoperative cognitive functionality. Its protective effect likely involves multi-target mechanisms, including stabilization complex modulation of the systemic immune response, rather than dependence on simple suppression of a single inflammatory pathway. This study provides a foundation for the clinical application of oxiracetam as a perioperative brain protection strategy for elderly surgical patients. |
| Publish Date |
2026-04-24 10:11 |
| Citation |
Lv BS, Wang W, Jin M, Ma Y, Wang JL, Gao H. Impact of oxiracetam on postoperative delirium in elderly patients undergoing laparoscopic gastrointestinal surgery. World J Gastrointest Surg 2026; 18(4): 119293 |
| URL |
https://www.wjgnet.com/1948-9366/full/v18/i4/119293.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v18.i4.119293 |
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