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5/12/2026 1:48:14 AM | Browse: 24 | Download: 32
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2026-05-12 01:37 |
| ISSN |
1948-5190 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Rethinking Helicobacter pylori-associated gastroduodenal disease through a systemic immune lens
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nebojsa Manojlovic and Stevan Manojlovic |
| Funding Agency and Grant Number |
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| Corresponding Author |
Nebojsa Manojlovic, Full Professor, MD, PhD, Clinic for Gastroenterology and Hepatology, Military Medical Academy, Medical Faculty of MMA, Crnotravska 17, Belgrade 11000, Serbia. nebojsa.manojlovic1@gmail.com |
| Key Words |
Helicobacter pylori; Systemic immunity; Immune imprinting; Gastritis; Duodenal ulcer; Cytokine signatures |
| Core Tip |
Emerging evidence suggests that Helicobacter pylori-associated gastroduodenal diseases are shaped not only by local mucosal inflammation but also by stable, phenotype-specific systemic immune states. Recent findings indicate that bacterial eradication induces distinct systemic immune recalibration in gastritis and duodenal ulcer, particularly involving regulatory pathways such as interleukin-10 signaling. Recognizing this systemic immune dimension may refine the interpretation of immunological data and inform future research beyond a purely gastric framework. |
| Publish Date |
2026-05-12 01:37 |
| Citation |
Manojlovic N, Manojlovic S. Letter to the Editor: Rethinking Helicobacter pylori-associated gastroduodenal disease through a systemic immune lens. World J Gastrointest Endosc 2026; 18(5): 119973 |
| URL |
https://www.wjgnet.com/1948-5190/full/v18/i5/119973.htm |
| DOI |
https://dx.doi.org/10.4253/wjge.v18.i5.119973 |
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