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5/12/2026 1:48:14 AM | Browse: 24 | Download: 32
Publication Name World Journal of Gastrointestinal Endoscopy
Manuscript ID 119973
Country Serbia
Received
2026-02-24 08:26
Peer-Review Started
2026-02-24 08:27
First Decision by Editorial Office Director
2026-03-06 09:21
Return for Revision
2026-03-06 09:21
Revised
2026-03-10 23:35
Publication Fee Transferred
Second Decision by Editor
2026-04-07 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-07 10:01
Articles in Press
2026-04-07 10:01
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-07 01:34
Publish the Manuscript Online
2026-05-12 01:37
ISSN 1948-5190 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Correspondence
Article Title Letter to the Editor: Rethinking Helicobacter pylori-associated gastroduodenal disease through a systemic immune lens
Manuscript Source Invited Manuscript
All Author List Nebojsa Manojlovic and Stevan Manojlovic
Funding Agency and Grant Number
Corresponding Author Nebojsa Manojlovic, Full Professor, MD, PhD, Clinic for Gastroenterology and Hepatology, Military Medical Academy, Medical Faculty of MMA, Crnotravska 17, Belgrade 11000, Serbia. nebojsa.manojlovic1@gmail.com
Key Words Helicobacter pylori; Systemic immunity; Immune imprinting; Gastritis; Duodenal ulcer; Cytokine signatures
Core Tip Emerging evidence suggests that Helicobacter pylori-associated gastroduodenal diseases are shaped not only by local mucosal inflammation but also by stable, phenotype-specific systemic immune states. Recent findings indicate that bacterial eradication induces distinct systemic immune recalibration in gastritis and duodenal ulcer, particularly involving regulatory pathways such as interleukin-10 signaling. Recognizing this systemic immune dimension may refine the interpretation of immunological data and inform future research beyond a purely gastric framework.
Publish Date 2026-05-12 01:37
Citation

Manojlovic N, Manojlovic S. Letter to the Editor: Rethinking Helicobacter pylori-associated gastroduodenal disease through a systemic immune lens. World J Gastrointest Endosc 2026; 18(5): 119973

URL https://www.wjgnet.com/1948-5190/full/v18/i5/119973.htm
DOI https://dx.doi.org/10.4253/wjge.v18.i5.119973
Full Article (PDF) WJGE-18-119973-with-cover.pdf
Manuscript File 119973_Auto_Edited_094024.docx
Answering Reviewers 119973-answering-reviewers.pdf
Audio Core Tip 119973-audio.m4a
Conflict-of-Interest Disclosure Form 119973-conflict-of-interest-statement.pdf
Copyright License Agreement 119973-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119973-non-native-speakers.pdf
Peer-review Report 119973-peer-reviews.pdf
Scientific Misconduct Check 119973-scientific-misconduct-check.png
Scientific Editor Work List 119973-scientific-editor-work-list.pdf
CrossCheck Report 119973-crosscheck-report.pdf