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9/20/2026 7:29:53 AM | Browse: 2 | Download: 0
Publication Name World Journal of Experimental Medicine
Manuscript ID 120424
Country Indonesia
Received
2026-02-27 03:21
Peer-Review Started
2026-02-27 03:21
First Decision by Editorial Office Director
2026-03-03 09:29
Return for Revision
2026-03-03 09:29
Revised
2026-03-06 05:45
Publication Fee Transferred
Second Decision by Editor
2026-06-11 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-11 08:28
Articles in Press
2026-06-11 08:28
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-30 12:15
Publish the Manuscript Online
2026-09-20 03:29
ISSN 2220-315x (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Research & Experimental Medicine
Manuscript Type Observational Study
Article Title Bacterial load and transforming growth factor-beta: Predicting the extent of lung damage in pulmonary tuberculosis patients
Manuscript Source Invited Manuscript
All Author List Putri Nila Kandi, M Harun Iskandar, Harry Akza Putrawan, Risna Halim Mubin, Syakib Bakri, Hasyim Kasim, Suriani Alimuddin, Resha Dermawansyah Rusman and Arifin Seweng
Funding Agency and Grant Number
Corresponding Author Putri Nila Kandi, MD, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Jl. Perintis Kemerdekaan KM 11, Makassar 90245, Sulawesi Selatan, Indonesia. putrinilaakandi@gmail.com
Key Words Pulmonary tuberculosis; Rapid molecular test; Bacterial load; Transforming growth factor-beta; Radiological lesion
Core Tip Pulmonary tuberculosis (TB) severity is shaped by the interplay between bacterial burden and host immune responses. This study examined their association with radiological lesion extent in newly diagnosed patients. Bacterial load was significantly associated with moderate-extensive lung damage, whereas systemic transforming growth factor-β levels did not reflect disease severity, suggesting a more localized immune role in TB pathogenesis.
Publish Date 2026-09-20 03:29
Citation

Kandi PN, Iskandar MH, Putrawan HA, Mubin RH, Bakri S, Kasim H, Alimuddin S, Rusman RD, Seweng A. Bacterial load and transforming growth factor-beta: Predicting the extent of lung damage in pulmonary tuberculosis patients. World J Exp Med 2026; 16(3): 120424

URL https://www.wjgnet.com/2220-315x/full/v16/i3/120424.htm
DOI https://doi.org/10.5493/wjem.120424
Full Article (PDF) WJEM-16-120424-with-cover.pdf
STROBE Statement 120424-STROBE-statement.pdf
Manuscript File 120424_Auto_Edited_015542.docx
Answering Reviewers 120424-answering-reviewers.pdf
Audio Core Tip 120424-audio.mp3
Biostatistics Review Certificate 120424-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120424-conflict-of-interest-statement.pdf
Copyright License Agreement 120424-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120424-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120424-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 120424-non-native-speakers.pdf
Peer-review Report 120424-peer-reviews.pdf
Scientific Misconduct Check 120424-scientific-misconduct-check.png
CrossCheck Report 120424-crosscheck-report.pdf