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8/25/2026 6:44:44 AM | Browse: 32 | Download: 49
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Received |
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2026-03-02 03:06 |
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Peer-Review Started |
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2026-03-02 05:46 |
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2026-03-20 11:31 |
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2026-03-20 11:31 |
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Revised |
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2026-04-18 15:54 |
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2026-04-23 22:40 |
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Second Decision by Editor |
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2026-06-10 02:33 |
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Final Decision by Editorial Office Director |
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2026-06-10 08:11 |
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Articles in Press |
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2026-06-10 08:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-20 02:02 |
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Publish the Manuscript Online |
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2026-08-25 06:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Mohamed Kharief, Roz O’Byrne, Karl William, Mohammed Ali Hasabarsoul, Orla Tuohy and Ashraf Morcos |
| Funding Agency and Grant Number |
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| Corresponding Author |
Mohamed Kharief, MD, Department of Gastroenterology, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E, Ireland. mohdkharief@gmail.com |
| Key Words |
Chronic intestinal pseudo-obstruction; Anti-glutamic acid decarboxylase antibodies; Autoimmune dysmotility; Enteric neuropathy; Intravenous immunoglobulin; Rituximab; Case report |
| Core Tip |
Chronic intestinal pseudo-obstruction is a rare and diagnostically challenging disorder that may be associated with autoimmune mechanisms. This case highlights anti-glutamic acid decarboxylase antibody-associated dysautonomia presenting with gastrointestinal dysmotility and evolving insulin-dependent diabetes mellitus. It underscores the importance of considering autoimmune etiologies in unexplained chronic intestinal pseudo-obstruction and demonstrates the potential benefit of immunomodulatory therapy, including corticosteroids, intravenous immunoglobulin, and rituximab, in achieving sustained clinical improvement. |
| Publish Date |
2026-08-25 06:38 |
| Citation |
Kharief M, O’Byrne R, William K, Hasabarsoul MA, Tuohy O, Morcos A. Anti-glutamic acid decarboxylase autoimmunity presenting as chronic intestinal pseudo-obstruction with dysautonomia and late-onset autoimmune diabetes: A case report. World J Gastroenterol 2026; 32(36): 120568
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i36/120568.htm |
| DOI |
https://doi.org/10.3748/wjg.120568 |
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