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9/23/2026 10:20:41 AM | Browse: 11 | Download: 19
Publication Name World Journal of Clinical Oncology
Manuscript ID 124416
Country China
Received
2026-06-15 08:34
Peer-Review Started
2026-06-15 08:34
First Decision by Editorial Office Director
Return for Revision
2026-07-24 06:38
Revised
2026-08-05 23:57
Publication Fee Transferred
2026-09-01 09:14
Second Decision by Editor
2026-09-22 03:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-09-22 09:54
Articles in Press
2026-09-22 09:54
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-23 02:21
Publish the Manuscript Online
2026-09-23 08:57
ISSN 2218-4333 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Observational Study
Article Title Efficacy of two programmed cell death 1 combination regimens in recurrent and/or metastatic head and neck carcinoma: A real-world retrospective study
Manuscript Source Unsolicited Manuscript
All Author List Jia-Xin Wang, Tian-Xiao Wang, Yun-Tao Song, Guo-Hui Xu, Ya-Bing Zhang and Bin Zhang
Funding Agency and Grant Number
Corresponding Author Bin Zhang, Department of Head and Neck Surgery, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. docbinzhang@hotmail.com
Key Words Head and neck squamous cell carcinoma; Programmed cell death 1 inhibitor; Cetuximab; Anlotinib; Immuno-targeted therapy
Core Tip Programmed cell death 1 (PD-1) inhibitors combined with cetuximab or anlotinib exhibit distinct therapeutic profiles in recurrent and/or metastatic head and neck squamous cell carcinoma. In this real-world cohort study, PD-1 inhibitor plus cetuximab was associated with significantly prolonged overall survival, whereas PD-1 inhibitor plus anlotinib showed favorable tumor response and disease control. These distinct efficacy profiles may help inform individualized treatment selection for PD-1-based immunotherapy-targeted therapy combinations.
Publish Date 2026-09-23 08:57
Citation

Wang JX, Wang TX, Song YT, Xu GH, Zhang YB, Zhang B. Efficacy of two programmed cell death 1 combination regimens in recurrent and/or metastatic head and neck carcinoma: A real-world retrospective study. World J Clin Oncol 2026; 17(9): 124416

URL https://www.wjgnet.com/2218-4333/full/v17/i9/124416.htm
DOI https://doi.org/10.5306/wjco.124416
Full Article (PDF) WJCO-17-124416-with-cover.pdf
STROBE Statement 124416-STROBE-statement.pdf
Manuscript File 124416_Auto_Edited_024441.docx
Answering Reviewers 124416-answering-reviewers.pdf
Audio Core Tip 124416-audio.mp3
Biostatistics Review Certificate 124416-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 124416-conflict-of-interest-statement.pdf
Copyright License Agreement 124416-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 124416-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 124416-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 124416-non-native-speakers.pdf
Supplementary Material 124416-supplementary-material.pdf
Peer-review Report 124416-peer-reviews.pdf
Scientific Misconduct Check 124416-scientific-misconduct-check.png
CrossCheck Report 124416-crosscheck-report.pdf