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10/21/2026 7:25:05 AM | Browse: 3 | Download: 0
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Received |
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2026-06-26 07:57 |
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Peer-Review Started |
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2026-06-26 07:58 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2026-07-22 06:25 |
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Revised |
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2026-08-01 14:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-09-20 02:51 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-09-20 10:47 |
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Articles in Press |
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2026-09-20 10:47 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-29 10:07 |
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Publish the Manuscript Online |
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2026-10-21 02:09 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Gut microbiome in patients with cirrhosis and clinically significant portal hypertension: A pilot study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Giuseppe Colucci, Sonia Stella, Andrea Castagnetti, Laura Di Rito, Martina Lucà, Giulia Tosetti, Roberta D’Ambrosio and Pietro Lampertico |
| Funding Agency and Grant Number |
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| Corresponding Author |
Giuseppe Colucci, Associate Research Scientist, MD, Research Assistant Professor, Division of Gastroenterology and Hepatology, IRCCS Fondazione Ca’ Granda Ospedale Maggiore Policlinico, via F. Sforza 28, Milan 20122, Italy. giuseppe.colucci@guest.unimi.it |
| Key Words |
Microbiome; Cirrhosis; Portal hypertension; Dysbiosis; Biodiversity |
| Core Tip |
The gut-liver axis is affected in cirrhosis with clinically significant portal hypertension and may contribute to disease progression and liver decompensation. In a group of patients recruited in a pilot study, we detected significant differences in the intestinal microbiota and mycobiota compared to healthy controls, including the presence of specific pathobionts. Dietary modifications and the supplementation of specific pre and probiotics may help preventing disease progression in patients with cirrhosis and clinically significant portal hypertension. |
| Publish Date |
2026-10-21 02:09 |
| Citation |
Colucci G, Stella S, Castagnetti A, Di Rito L, Lucà M, Tosetti G, D’Ambrosio R, Lampertico P. Gut microbiome in patients with cirrhosis and clinically significant portal hypertension: A pilot study. World J Hepatol 2026; 18(10): 124666
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| URL |
https://www.wjgnet.com/1948-5182/full/v18/i10/124666.htm |
| DOI |
https://doi.org/10.4254/wjh.124666 |
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