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9/29/2014 8:05:00 AM | Browse: 525 | Download: 857
Publication Name World Journal of Stem Cells
Manuscript ID 12731
Country United Kingdom
Received
2014-07-23 20:19
Peer-Review Started
2014-07-24 17:24
To Make the First Decision
2014-08-28 14:41
Return for Revision
2014-08-29 14:15
Revised
2014-09-03 17:22
Second Decision
2014-09-17 14:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-09-17 14:36
Articles in Press
2014-09-17 14:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-09-22 17:37
Publish the Manuscript Online
2014-09-28 14:56
ISSN 1948-0210 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Minireviews
Article Title Cell signalling pathways underlying induced pluripotent stem cell reprogramming
Manuscript Source Invited Manuscript
All Author List Kate Hawkins, Shona Joy and Tristan McKay
Funding Agency and Grant Number
Corresponding Author Dr. Kate Hawkins, Molecular Cell Sciences, St George’s University of London, Cranmer Terrace, London, SW17 0RE, United Kingdom. k.hawkins@sgul.ac.uk
Key Words Pluripotency; Reprogramming; Induced pluripotent stem; Cell signalling; Embryonic stem
Core Tip Induced pluripotent stem (iPS) cells present great promise, both to research and to medicine. However, we know very little regarding the mechanisms that occur throughout the iPS cell reprogramming process and thus the process remains inefficient. In this review, we discuss the 3 stages of reprogramming, initiation, maturation and stabilisation, and clarify the signalling pathways underlying each phase. We draw together the current knowledge to propose a model for the interactions between the key pathways in iPS cell reprogramming with the aim of illuminating this complex yet fascinating process.
Publish Date 2014-09-28 14:56
Citation Hawkins K, Joy S, McKay T. Cell signalling pathways underlying induced pluripotent stem cell reprogramming. World J Stem Cells 2014; 6(5): 620-628
URL http://www.wjgnet.com/1948-0210/full/v6/i5/620.htm
DOI http://dx.doi.org/10.4252/wjsc.v6.i5.620
Full Article (PDF) WJSC-6-620.pdf
Full Article (Word) WJSC-6-620.doc
Manuscript File 12731-Review.docx
Answering Reviewers 12731-Answering reviewers.pdf
Copyright License Agreement 12731-Copyright assignment.pdf
Peer-review Report 12731-Peer review(s).pdf
Scientific Misconduct Check 12731-CrossCheck.jpg
Scientific Editor Work List 12731-Scientific editor work list.pdf