Publication Name	World Journal of Stem Cells
Manuscript ID	12976
Country	Spain

Received	2014-07-30 19:02
Peer-Review Started	2014-07-30 21:35
To Make the First Decision	2014-09-16 10:47
Return for Revision	2014-09-18 14:24
Revised	2014-11-13 23:14
Second Decision	2014-12-11 08:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-12-17 16:44
Articles in Press	2014-12-17 16:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-30 11:34
Publish the Manuscript Online	2015-04-23 12:08

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell Biology
Manuscript Type	Review
Article Title	Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cells
Manuscript Source	Invited Manuscript
All Author List	Amparo Beltran-Povea, Estefania Caballano-Infantes, Carmen Salguero-Aranda, Franz Martín, Bernat Soria, Francisco J Bedoya, Juan R Tejedo and Gladys M Cahuana
Funding Agency and Grant Number	Funding Agency Grant Number Consejería de Igualdad, Salud y Politicas Sociales, Junta de Andalucía PI105/2010 Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía CTS-7127/2011 (to Bedoya FJ) Consejería de Igualdad, Salud y Políticas Sociales, Junta de Andalucía, ISCIII co-funded by Fondos FEDER (RED TERCEL) RD06/0010/0025 Consejería de Igualdad, Salud y Políticas Sociales, Junta de Andalucía, ISCIII co-funded by Fondos FEDER (RED TERCEL) RD12/0019/0028 Consejería de Economía, Innovación, Ciencia y Empleo P10.CTS.6505 Ministry of Health and Consumer Affairs (Advanced Therapies Program Grant) TRA-120(to Soria B) Consejería de Igualdad, Salud y Políticas Sociales PI0022/2008 Consejería de Economía, Innovación, Ciencia y Empleo, Junta de Andalucía PAI, BIO311(to Martín F) Servicio Andaluz de Salud SAS 11245 Ministerio de Economía y Competitividad-Secretaría de Estado de Investigación Desarrollo e Innovación IPT-2011-1615-900000 (to Tejedo JR)
Corresponding Author	Gladys M Cahuana, PhD, Andalusian Center for Molecular Biology and Regenerative Medicine-University Pablo de Olavide, Av. Américo Vespucio s/n-Edif, CABIMER, Parque Científico y Tecnológico Cartuja 93, 41092 Seville, Spain. gmcahmac@upo.es
Key Words	Pluripotency; Differentiation; Nitric oxide; Metabolism; Hypoxia; Stem cell
Core Tip	Increasing research interest has focused on the role of nitric oxide (NO) in regulating many physiological functions such as metabolism, the hypoxia response, pluripotency, and stem cell differentiation. NO has been proven to act as a powerful agent for promoting the maintenance of cell pluripotency and survival, thus explaining how it can act as an alternative factor for the maintenance of certain cultured cell lines.
Publish Date	2015-04-23 12:08
Citation	Beltran-Povea A, Caballano-Infantes E, Salguero-Aranda C, Martín F, Soria B, Bedoya FJ, Tejedo JR, Cahuana GM. Role of nitric oxide in the maintenance of pluripotency and regulation of the hypoxia response in stem cells. World J Stem Cells 2015; 7(3): 605-617
URL	http://www.wjgnet.com/1948-0210/full/v7/i3/605.htm
DOI	http://dx.doi.org/10.4252/wjsc.v7.i3.605

Full Article (PDF)	WJSC-7-605.pdf
Full Article (Word)	WJSC-7-605.doc
Manuscript File	12976-Review.docx
Answering Reviewers	12976-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	12976-Conflict-of-interest statement.pdf
Copyright License Agreement	12976-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	12976-Language certificate.pdf
Peer-review Report	12976-Peer review(s).pdf
Scientific Misconduct Check	12976-CrossCheck.jpg
Scientific Editor Work List	12976-Scientific editor work list.pdf