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12/13/2014 6:17:00 PM | Browse: 510 | Download: 1310
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Received |
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2014-09-01 09:19 |
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Peer-Review Started |
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2014-09-04 08:07 |
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To Make the First Decision |
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2014-09-28 13:55 |
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Return for Revision |
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2014-09-30 11:48 |
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Revised |
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2014-10-14 00:14 |
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Second Decision |
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2014-10-30 16:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-11-10 16:10 |
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Articles in Press |
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2014-11-10 16:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-12-03 20:04 |
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Publish the Manuscript Online |
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2014-12-13 17:50 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Vitamin D deficiency in chronic liver disease
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Manuscript Source |
Invited Manuscript |
All Author List |
Paula Iruzubieta, Álvaro Terán, Javier Crespo and Emilio Fábrega |
Funding Agency and Grant Number |
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Corresponding Author |
Emilio Fábrega, MD, Gastroenterology and Hepatology Unit, Marqués de Valdecilla University Hospital, Instituto de Investigación Marqués de Valdecilla, Avenida Valdecilla s/n, 39008 Santander, Cantabria, Spain. digfge@humv.es
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Key Words |
Cholecalciferol; Vitamin D; Hepatitis C; Liver fibrosis; Liver disease; Interferon; Sustained virological response; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis |
Core Tip |
(Vitamin D and liver disease) vitamin D deficiency has been frequently reported in many causes of chronic liver disease and has been associated with the development and evolution of non-alcoholic fatty liver disease (NAFLD) and chronic hepatitis C (CHC) virus infection. The role of vitamin D in the pathogenesis of NAFLD and CHC is not completely known, but it seems that the involvement of vitamin D in the activation and regulation of both innate and adaptive immune systems and its antiproliferative effect may explain its importance in these liver diseases.
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Publish Date |
2014-12-13 17:50 |
Citation |
Iruzubieta P, Terán Á, Crespo J, Fábrega E. Vitamin D deficiency in chronic liver disease. World J Hepatol 2014; 6(12): 901-915 |
URL |
http://www.wjgnet.com/1948-5182/full/v6/i12/901.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v6.i12.901 |
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