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6/19/2015 5:32:00 PM | Browse: 662 | Download: 1456
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Received |
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2014-09-09 14:52 |
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Peer-Review Started |
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2014-09-09 20:34 |
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To Make the First Decision |
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2014-12-17 11:19 |
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Return for Revision |
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2014-12-19 11:47 |
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Revised |
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2014-12-21 09:50 |
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Second Decision |
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2015-03-09 09:17 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-03-18 16:31 |
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Articles in Press |
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2015-03-18 16:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-05-27 17:41 |
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Publish the Manuscript Online |
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2015-06-19 17:20 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Review |
Article Title |
Recent progress in the genetics of diabetic microvascular complications
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Manuscript Source |
Invited Manuscript |
All Author List |
Yi-Cheng Chang, Emily Yun-Chia Chang and Lee-Ming Chuang |
Funding Agency and Grant Number |
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Corresponding Author |
Dr. Lee-Ming Chuang, MD, PhD, Department of Internal Medicine, National Taiwan University Hospital, 7, Chung Shan S. Rd, Taipei 100, Taiwan. leeming@ntu.edu.tw |
Key Words |
Microvascular complications; Nephropathy; Retionopathy; Neuropathy; Diabetes |
Core Tip |
Most risk genetic loci identified by genome-wide association studies (GWAS) for diabetic nephropathy could not be replicated by independent studies with a few exceptions including those in ELMO1, FRMD3, CARS, MYO16/IRS2, and APOL3-MYH9 genes. These findings highlighted the importance of cytoskeleton reorganization, phagocytosis of apoptotic cells, fibroblast migration, insulin signaling, and epithelial clonal expansion in the pathogenesis of diabetic nephropathy. Conclusive results from GWAS for diabetic retinopathy and diabetic neuropathy are currently lacking. |
Publish Date |
2015-06-19 17:20 |
Citation |
Chang YC, Chang EYC, Chuang LM. Recent progress in the genetics of diabetic microvascular complications. World J Diabetes 2015; 6(5): 715-725 |
URL |
http://www.wjgnet.com/1948-9358/full/v6/i5/715.htm |
DOI |
http://dx.doi.org/10.4239/wjd.v6.i5.715 |
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