Publication Name	World Journal of Stem Cells
Manuscript ID	14372
Country	France

Received	2014-09-30 08:40
Peer-Review Started	2014-10-01 11:47
To Make the First Decision	2014-10-28 14:34
Return for Revision	2014-10-30 18:32
Revised	2014-11-13 20:51
Second Decision	2014-12-23 20:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-12-31 13:44
Articles in Press	2014-12-31 13:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-31 09:58
Publish the Manuscript Online	2015-04-23 12:08

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Use of human pluripotent stem cells to study and treat retinopathies
Manuscript Source	Invited Manuscript
All Author List	Karim Ben M’Barek, Florian Regent and Christelle Monville
Funding Agency and Grant Number
Corresponding Author	Christelle Monville, PhD, INSERM UMR861, I-Stem, AFM, 5 rue Henri Desbruères, Genopole Campus 1, 91030 Evry, France. cmonville@istem.fr
Key Words	Drug screening; Human pluripotent stem cells; Disease modeling; Retinitis pigmentosa
Core Tip	Human pluripotent stem cells (hPSCs) are usually evoked for their potential for regenerative medicine. However, beside these aspects, novel interests raise from the potential of hPSCs to model human diseases including retinopathies. In this review, we describe how these cells allow the study of the molecular mechanisms leading to some form of retinopathies through the development of retinal specific cell type derived from the differentiation of hPSCs. We also discuss the use of hPSCs cellular models for the validation of gene therapy and for drug screening purpose.
Publish Date	2015-04-23 12:08
Citation	Ben M’Barek K, Regent F, Monville C. Use of human pluripotent stem cells to study and treat retinopathies. World J Stem Cells 2015; 7(3): 596-604
URL	http://www.wjgnet.com/1948-0210/full/v7/i3/596.htm
DOI	http://dx.doi.org/10.4252/wjsc.v7.i3.596

Full Article (PDF)	WJSC-7-596.pdf
Full Article (Word)	WJSC-7-596.doc
Manuscript File	14372-Review.docx
Answering Reviewers	14372-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14372-Conflict-of-i nterest statement.pdf
Copyright License Agreement	14372-Copyright assignment.pdf
Peer-review Report	14372-Peer review(s).pdf
Scientific Misconduct Check	14372-CrossCheck.jpg
Scientific Editor Work List	14372-Scientific editor work list.pdf