Publication Name	World Journal of Hepatology
Manuscript ID	14993
Country	Greece

Received	2014-11-03 08:14
Peer-Review Started	2014-11-03 19:06
To Make the First Decision	2014-11-27 12:22
Return for Revision	2014-12-04 10:38
Revised	2014-12-13 02:53
Second Decision	2015-01-08 16:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-01-19 13:33
Articles in Press	2015-01-19 13:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-03-30 10:25
Publish the Manuscript Online	2015-04-14 18:13

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Non-invasive methods for the diagnosis of nonalcoholic fatty liver disease
Manuscript Source	Invited Manuscript
All Author List	Marianthi Papagianni, Areti Sofogianni and Konstantinos Tziomalos
Funding Agency and Grant Number
Corresponding Author	Konstantinos Tziomalos, MD, PhD, First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Kiriakidi 1, 54636 Thessaloniki, Greece. ktziomalos@yahoo.com
Key Words	Nonalcoholic steatohepatitis; Steatosis; Fibrosis; Imaging; Nonalcoholic fatty liver disease
Core Tip	Current data suggest that ultrasound and the fibrosis-4 score are probably the most appealing methods for detecting steatosis and for distinguishing nonalcoholic steatohepatitis from simple steatosis, respectively, because of their low cost and relatively high accuracy. However, currently available methods, both serologic and imaging, cannot obviate the need for liver biopsy for diagnosing nonalcoholic steatohepatitis due to their substantial false positive and false negative rates. Therefore, the current role of these methods is probably limited in patients who are unwilling or have contraindications for undergoing biopsy.
Publish Date	2015-04-14 18:13
Citation	Papagianni M, Sofogianni A, Tziomalos K. Non-invasive methods for the diagnosis of nonalcoholic fatty liver disease. World J Hepatol 2015; 7(4): 638-648
URL	http://www.wjgnet.com/1948-5182/full/v7/i4/638.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i4.638

Full Article (PDF)	WJH-7-638.pdf
Full Article (Word)	WJH-7-638.doc
Manuscript File	14993-Review.docx
Answering Reviewers	14993-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14993-Conflict-of-interest statement.pdf
Copyright License Agreement	14993-Copyright assignment.pdf
Peer-review Report	14993-Peer review(s).pdf
Scientific Misconduct Check	14993-CrossCheck.jpg
Scientific Editor Work List	14993-Scientific editor work list.pdf