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8/4/2015 11:51:00 AM | Browse: 679 | Download: 1727
Publication Name World Journal of Immunology
Manuscript ID 15758
Country/Territory Israel
Received
2014-12-08 09:39
Peer-Review Started
2014-12-09 09:38
To Make the First Decision
2014-12-26 13:10
Return for Revision
2015-01-03 16:56
Revised
2015-01-14 16:31
Second Decision
2015-02-26 17:38
Accepted by Journal Editor-in-Chief
2015-02-27 01:25
Accepted by Company Editor-in-Chief
2015-06-08 15:58
Articles in Press
2015-06-08 16:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-07-07 14:37
Publish the Manuscript Online
2015-08-04 10:49
ISSN 2219-2824 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title GRP78 expression beyond cellular stress: A biomarker for tumor manipulation
Manuscript Source Invited Manuscript
All Author List Britta Hardy and Annat Raiter
Funding Agency and Grant Number
Corresponding Author Britta Hardy, PhD, Professor, Director, Felsenstein Medical Research Center, Tel-Aviv University School of Medicine, Rabin Medical Center, Beilinson Campus, Petach Tikva 49100, Israel. brittah23@gmail.com
Key Words Cell surface GRP78; Apoptosis; Endoplasmic reticulum stress; Tumor cells; Cancer; Cardiovascular ischemia; Hypoxia
Core Tip In the prolonged chronic stress transportation of the GRP78 from the endoplasmic reticulum to the cell membrane is a major event where in addition to the presentation of the GRP78 as a receptor to various ligands, it also marks the cells that will proceed to apoptotic pathways. In the normal cell that under stress acquires cell surface GRP78 and in the tumor cell that already presents cell surface GRP78, cell surface GRP78 is an apoptotic flag. This review analyzes the input of cell surface GRP78 on apoptosis in normal and tumor cells.
Publish Date 2015-08-04 10:49
Citation Hardy B , Raiter A. GRP78 expression beyond cellular stress: A biomarker for tumor manipulation. World J Immunol 2015; 5(2): 78-85
URL http://www.wjgnet.com/2219-2824/full/v5/i2/78.htm
DOI http://dx.doi.org/10.5411/wji.v5.i2.78
Full Article (PDF) WJI-5-78.pdf
Full Article (Word) WJI-5-78.doc
Manuscript File 15758-Review.docx
Answering Reviewers 15758-Answering reviewers.pdf
Audio Core Tip 15758-Audio core tip.aiff
Conflict-of-Interest Disclosure Form 15758-Conflict-of-interest statement.pdf
Copyright License Agreement 15758-Copyright assignment.pdf
Peer-review Report 15758-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 15758-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 15758-Scientific misconduct check.pdf
Scientific Editor Work List 15758-Scientific editor work list.pdf