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4/30/2015 2:53:00 PM | Browse: 833 | Download: 1948
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Received |
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2014-12-21 11:43 |
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Peer-Review Started |
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2014-12-21 16:09 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2015-01-30 16:58 |
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Revised |
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2015-02-11 19:16 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2015-03-04 18:42 |
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Second Decision by Editor-in-Chief |
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2015-03-05 00:20 |
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Final Decision by Editorial Office Director |
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2015-03-12 16:32 |
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Articles in Press |
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2015-03-12 16:46 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-04-03 15:53 |
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Publish the Manuscript Online |
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2015-04-20 15:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Management of hepatitis C infection before and after liver transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Stefano Fagiuoli, Roberto Ravasio, Maria Grazia Lucà, Anna Baldan, Silvia Pecere, Alessandro Vitale and Luisa Pasulo |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Stefano Fagiuoli, USC, Gastroenterology and Transplant Hepatology, Papa Giovanni XXIII Hospital, Piazza OMS, 1, 24127 Bergamo, Italy. sfagiuoli@hpg23.it |
| Key Words |
Hepatitis C virus; Orthotopic liver transplantation; Interferon-free treatment; Decompensated cirrhosis; Chronic hepatitis C |
| Core Tip |
This paper discusses alternative treatment options for patients with hepatitis C virus (HCV) undergoing liver transplantation (LT), particularly those with decompensated cirrhosis in whom interferon (IFN)-based therapy is contraindicated. Virtually all patients undergoing LT experience HCV recurrence leading to accelerated liver disease and cirrhosis development with reduced graft and patient survival. Novel IFN-free antiviral therapies featuring better efficacy and tolerability in such patients shall increase sustained virologic response rates while decreasing side effects and drug interactions, thus preventing progression of HCV-related liver disease, decreasing the general costs associated with both HCV treatment and worsening of patient health. |
| Publish Date |
2015-04-20 15:10 |
| Citation |
Fagiuoli S, Ravasio R, Lucà MG, Baldan A, Pecere S, Vitale A, Pasulo L. Management of hepatitis C infection before and after liver transplantation. World J Gastroenterol 2015; 21(15): 4447-4456
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| URL |
http://www.wjgnet.com/1007-9327/full/v21/i15/4447.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i15.4447 |
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